Scanning electrochemical microscopy studies of cells: transport, viability and communication
Scanning electrochemical microscopy studies of cells: transport, viability and communication
批准号:
312503-2008
负责人:
Mauzeroll, Janine
金额:
$2.62万
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2009
资助国家:
加拿大
项目状态:
已结题
起止时间:
2009-01-01 至 2010-12-31
中文摘要
扫描电化学显微镜(SECM)是有用的,因为它探测表面的化学或生化活性。它是通过测量传感器的电流来实现的,该传感器使用精确的定位器向样品移动或在样品上方移动。这种特殊的检测方法可以检测被癌细胞吸收或释放的小浓度化合物。为了将SECM应用于活细胞研究,细胞必须固定在固体支架上。传感器被非侵入性地放置在其上方几微米处。然后用一种化学物质刺激细胞,释放出可以被SECM直接检测到的化合物。通过这些测量和数值模拟,可以提取与这些事件有关的输运速率和动力学参数
英文摘要
Scanning Electrochemical Microscopy (SECM) is useful because it probes the chemical or biochemical activity of a surface. It does so by measuring a current at a sensor that is moved towards or over a sample using precise positioners. This specific detection method can detect small concentrations of compounds being absorbed or released from cancer cells. To apply SECM to live cell studies, cells have to be immobilized on a solid support. The sensor is positioned non-invasively a few microns above it. The cells are then stimulated by a chemical to release compounds that can directly be detected by SECM. From such measurements and using numerical simulations, the rates of transport and kinetic parameters related to these events can be extracted
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批准号:RGPIN-2020-04609
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项目类别:Discovery Grants Program - Individual
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资助金额:$4.66万
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财政年份:2022
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负责人:Mauzeroll, Janine
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依托单位:
Using dynamic flow electrolysis and mechanochemistry to enhance the performance of gold production.
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批准号:566913-2021
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项目类别:Alliance Grants
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资助金额:$11.82万
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依托单位:
Development of pH-responsive carriers for the controlled release of encapsulated acidifying and antibacterial agents
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批准号:531450-2018
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项目类别:Collaborative Research and Development Grants
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资助金额:$4.07万
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财政年份:2021
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依托单位:
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批准号:RGPIN-2020-04609
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项目类别:Discovery Grants Program - Individual
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资助金额:$4.66万
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财政年份:2021
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负责人:Mauzeroll, Janine
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依托单位:
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批准号:RGPIN-2020-04609
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项目类别:Discovery Grants Program - Individual
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资助金额:$4.66万
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财政年份:2020
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依托单位:
Low Current Scanning Electrochemical Microscope for Reactive Imaging of Energy and Structural Materials
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批准号:RTI-2021-00153
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项目类别:Research Tools and Instruments
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资助金额:$10.93万
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财政年份:2020
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负责人:Mauzeroll, Janine
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依托单位:
Development of pH-responsive carriers for the controlled release of encapsulated acidifying and antibacterial agents.
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批准号:531450-2018
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项目类别:Collaborative Research and Development Grants
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资助金额:$4.07万
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财政年份:2020
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负责人:Mauzeroll, Janine
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依托单位:
Development of pH-responsive carriers for the controlled release of encapsulated acidifying and antibacterial agents.
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批准号:531450-2018
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项目类别:Collaborative Research and Development Grants
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资助金额:$4.07万
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财政年份:2019
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负责人:Mauzeroll, Janine
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依托单位:
Developing High Speed Scanning Electrochemical Microscopy of Biological Substrates
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批准号:RGPIN-2015-06054
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.28万
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财政年份:2019
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负责人:Mauzeroll, Janine
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依托单位:
Developing High Speed Scanning Electrochemical Microscopy of Biological Substrates
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批准号:RGPIN-2015-06054
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.28万
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财政年份:2018
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负责人:Mauzeroll, Janine
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依托单位:
Surface engineering of advanced composite coatings for significant enhancement to the life cycle of HydroPower infrastructure
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批准号:478885-2015
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项目类别:Strategic Projects - Group
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资助金额:$10.45万
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财政年份:2017
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负责人:Mauzeroll, Janine
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依托单位:
Developing High Speed Scanning Electrochemical Microscopy of Biological Substrates
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批准号:RGPIN-2015-06054
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.28万
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财政年份:2017
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负责人:Mauzeroll, Janine
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依托单位:
Developing High Speed Scanning Electrochemical Microscopy of Biological Substrates
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批准号:RGPIN-2015-06054
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.28万
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财政年份:2016
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负责人:Mauzeroll, Janine
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依托单位:
Surface engineering of advanced composite coatings for significant enhancement to the life cycle of HydroPower infrastructure
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批准号:478885-2015
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项目类别:Strategic Projects - Group
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资助金额:$10.45万
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财政年份:2016
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负责人:Mauzeroll, Janine
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依托单位:
Surface engineering of advanced composite coatings for significant enhancement to the life cycle of HydroPower infrastructure
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批准号:478885-2015
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项目类别:Strategic Projects - Group
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资助金额:$10.24万
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财政年份:2015
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负责人:Mauzeroll, Janine
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依托单位:
Phase 1 : manufacturing of flow systems and microelectrodes having a controlled geometry.
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批准号:486879-2015
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资助金额:$8.89万
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财政年份:2015
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负责人:Mauzeroll, Janine
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依托单位:
Developing High Speed Scanning Electrochemical Microscopy of Biological Substrates
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批准号:RGPIN-2015-06054
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.28万
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财政年份:2015
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负责人:Mauzeroll, Janine
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依托单位:
Evaluating the use of N-heterocyclic carbenes in corrosion resistant coatings for aluminum and magnesium alloys
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批准号:463347-2014
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资助金额:$10.34万
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财政年份:2015
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负责人:Mauzeroll, Janine
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依托单位:
Predicting corrosion of magnesium alloys with complex microstructure and reactivity
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批准号:402825-2010
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项目类别:Collaborative Research and Development Grants
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资助金额:$14.26万
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财政年份:2015
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负责人:Mauzeroll, Janine
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依托单位:
Evaluating the use of N-heterocyclic carbenes in corrosion resistant coatings for aluminum and magnesium alloys
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批准号:463347-2014
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项目类别:Strategic Projects - Group
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资助金额:$12.73万
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财政年份:2014
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负责人:Mauzeroll, Janine
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依托单位:
国内基金
海外基金
电极/溶液界面上分子取向电位调控的准确测量
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批准号:20373076
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项目类别:面上项目
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资助金额:27.0万元
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批准年份:2003
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负责人:王鸿飞
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依托单位: