TSLP and dysregulation of anti-viral immunity in atopic dermatitis

湿疹（特应性皮炎）是澳大利亚常见的过敏症。患有湿疹的人可能会受到一些病毒的严重皮肤感染，包括导致唇疱疹的病毒，但我们不知道为什么会发生这种情况。一种新发现的名为TSLP的蛋白质现在已知是由受湿疹影响的皮肤产生的，有证据表明TSLP可能会干扰身体对抗病毒的方式。我们将检查TSLP是否会对免疫系统进行编程，从而降低其对抗病毒的能力。

Eczema (atopic dermatitis) is a frequent allergy in Australia. People with eczema can suffer very severe skin infections with some viruses, including the virus that causes cold sores, but we do not know why this happens. A newly discovered protein called TSLP is now known to be made by skin affected by eczema and there is evidence that TSLP may interfere with the way the body fights viruses. We will examine whether TSLP programs the immune system so that it is less able to fight viruses.