Motor performance and the influence of neuromuscular fatigue in knee osteoarthritis

膝关节骨关节炎会导致慢性疼痛，限制行动能力，降低成千上万加拿大人的生活质量。 医疗费用加重了这一负担-加拿大每年花费超过44亿美元用于治疗膝关节骨关节炎。 日常活动中施加在膝关节上的负荷是触发和促进膝关节炎的关键。 然而，我们对日常活动引起的疲劳如何影响这种负荷环境知之甚少。 该研究项目评估了疲劳对膝关节负荷的影响。

Knee osteoarthritis causes chronic pain, limits mobility and reduces quality of life for thousands of Canadians. This burden is compounded by healthcare costs - over $4.4 billion is spent every year in Canada to manage knee osteoarthritis. The loads placed on the knee during daily activities are critical in triggering and facilitating knee arthritis. However, we know very little about how fatigue induced by daily activities contributes to this loading environment. This research program evaluates the influence of fatigue on the loads placed on the knee.