Understanding the Role of MAIT cells in health and Disease

一组特殊的T淋巴细胞被称为粘膜相关不变T细胞(MAIT)，它可以保护我们免受细菌和酵母菌的侵害，这些细胞位于人体免疫系统最容易被破坏的粘膜部位，例如肠道、口腔、呼吸道和生殖道。这项研究调查了MAIT细胞在健康以及炎症性肠病、消化性溃疡、牙周炎和结核病等疾病中的作用。控制MAIT细胞可以帮助治疗这些疾病。

A specialised set of T lymphocytes called Mucosal Associated Invariant T (MAIT) cells protect us from bacteria and yeast at mucosal sites where the body's immune defences are most easily breached, e.g. gut, oral cavity, airways & reproductive tract. This study investigates the role of MAIT cells in health and in diseases like inflammatory bowel disease, peptic ulceration, periodontitis and tuberculosis. Controlling MAIT cells could help in treating these conditions.