Understanding sperm motility for infertility and contraceptive purposes
Understanding sperm motility for infertility and contraceptive purposes
批准号:
nhmrc : 1029144
负责人:
A/Pr Mark Baker
金额:
$30.12万
依托单位国家:
澳大利亚
项目类别:
Career Development Fellowships
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2016-12-31
中文摘要
男性不育症是一个严重的临床问题,每20名澳大利亚男性中就有一人受到影响。与这种情况相关的最常见的特征是精子运动能力的缺陷。精子运动的调节是通过附睾和射精来实现的。这项研究将研究两种对鞭毛弯曲至关重要的激酶是如何调节精子活力的。通过开发的工具,我们将进一步调查精子活力受损的不育患者的缺陷。
英文摘要
Male infertility is a significant clinical problem affecting one in twenty Australian men. The most common feature associated with this condition is defects in sperm motility. Regulation of sperm motility occurs through the epididymis and upon ejaculation. This study will examine how two kinases, essential for flagella bending, regulate sperm motility. Through the tools developed, we will investigate further defectives in infertile individuals with impaired sperm motility.
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会议论文
Biomarkers for the Diagnosis and Prognostic Analysis of Male Infertility
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批准号:nhmrc : 1118943
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项目类别:Research Fellowships
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资助金额:$43.17万
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财政年份:2017
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负责人:A/Pr Mark Baker
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依托单位:
Biomarkers for the Diagnosis and Prognostic Analysis of Male Infertility
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批准号:nhmrc : GNT1118943
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项目类别:Research Fellowships
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资助金额:$63.14万
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财政年份:2017
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负责人:A/Pr Mark Baker
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依托单位:
Understanding idiopathic male infertility: Biomarkers to assist in the diagnosis and assisted reproductive technology outcomes
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批准号:nhmrc : GNT1101615
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项目类别:Project Grants
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资助金额:$41.1万
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财政年份:2016
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负责人:A/Pr Mark Baker
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依托单位:
Understanding idiopathic male infertility: Biomarkers to assist in the diagnosis and assisted reproductive technology outcomes
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批准号:nhmrc : 1101615
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项目类别:Project Grants
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资助金额:$28.17万
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财政年份:2016
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负责人:A/Pr Mark Baker
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依托单位:
Characterising a newly identified mechanism causing elevation of intracranial pressure after acute neurological injury
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批准号:nhmrc : 1085450
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项目类别:Project Grants
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资助金额:$34.07万
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财政年份:2015
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负责人:A/Pr Mark Baker
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依托单位:
Izumo1 and its role in male infertility and male contraception
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批准号:nhmrc : 1084750
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项目类别:Project Grants
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资助金额:$21.16万
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财政年份:2015
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负责人:A/Pr Mark Baker
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依托单位:
Izumo1 and its role in male infertility and male contraception
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批准号:nhmrc : GNT1084750
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项目类别:Project Grants
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资助金额:$20.48万
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财政年份:2015
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负责人:A/Pr Mark Baker
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依托单位:
Understanding the Molecular Basis of Epididymal Maturation: How Does the Epididymis Modify Spermatozoa, Allowing them to Recognise the Egg ?
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批准号:nhmrc : 1010753
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项目类别:Project Grants
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资助金额:$39.07万
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财政年份:2011
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负责人:A/Pr Mark Baker
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依托单位:
Identification and characterisation of phosphorylation events taking place during human sperm capacitation
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批准号:nhmrc : 569258
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项目类别:NHMRC Project Grants
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资助金额:$18.7万
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财政年份:2009
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负责人:A/Pr Mark Baker
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依托单位:
国内基金
海外基金
副睾ELP16基因的功能研究
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批准号:30670448
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项目类别:面上项目
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资助金额:30.0万元
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批准年份:2006
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负责人:金由辛
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依托单位: