Digital gel documentations system for comparative immunology group

在此，我们要求为比较免疫学小组提供凝胶文件系统。比较免疫学或对动物免疫过程的研究通常是通过免疫基因的表达来衡量的。我们研究的许多组成部分都涉及可视化DNA片段。DNA与一种染料混合，这种染料非常专门地与DNA结合，当DNA被紫外光照射时，会发出明亮的红色。因此，波段可以在UV盒(透光器)上显示出来。这些乐队的照片可以被永久记录下来。我们可以通过与已知标准的比较来确定基因片段的大小，或者通过分析条带的密度来确定基因表达的数量。我们还可以从凝胶中提取DNA来恢复基因，以研究其在细胞系中的功能。这使我们能够确定动物对疾病有机体的反应。该仪器将支持在该地区工作的所有比较免疫学家和微生物学家。我们的实验室正在研究鸭子是如何对抗流感病毒的，因为它们被感染了，但没有受到杀死鸡、猪和人类的病毒的伤害。另一个项目通过研究鱼类中的系统，研究了用于抗体多样性的基因突变体的调节。

Here we request a Gel documentation system for the Comparative Immunology Group. Comparative immunology, or the study of immune processes in animals is often measured by the expression of immune genes. Many components of our research involve visualizing DNA fragments. DNA is mixed with a dye that binds very specifically to the DNA, which when illuminated by UV light, shines bright red. Thus bands can be visualized on a UV box (transilluminator). Photographs can be taken of these bands for a permanent record. We can determine the size of a gene fragment by comparison with known standards, or the amount of a gene expressed by analyzing the density of the band. We can also excise the DNA from the gel to recover the gene to study its function in cell lines. This allows us to determine the response of an animal to disease organisms. This instrument will support all comparative immunologists and microbiologists working in area. Our lab is studying how ducks fight the flu virus, since they are infected but unharmed by strains that kill chickens, pigs, and humans. Another program examines the regulation of the gene mutator used for antibody diversity, by studying the system in fish.