Using Metagenomics to Determine the Causative Agent(s) of Tick-Borne Disease in Australia

在澳大利亚，蜱传疾病已经成为一个热门和有争议的公共卫生问题。我们将采用最先进的宏基因组学技术来确定哪些微生物物种（细菌、病毒和真核生物）在澳大利亚蜱虫中传播，以及这些或其他微生物是否也存在于被诊断患有蜱传疾病的人体内。所产生的数据将提供关键信息，说明蜱传疾病是否有微生物原因，如果有，涉及的微生物。

Tick-borne disease has emerged as a topical and controversial public health problem in Australia. We will employ state-of-the-art techniques in metagenomics to determine what microbial species (bacteria, viruses and eukaryotes) circulate in Australian ticks and whether these or different microbes are also present in humans diagnosed with tick-borne disease. The data generated will provide key information on whether tick-borne disease has a microbiological cause and, if so, the microbes involved.