Vascular Biology

这一研究计划坚定地聚焦于细胞和组织正常功能所涉及的基本机制，随后是一个逐步了解异常或疾病的过程。我们正在调查的疾病状态涉及血管和血管，当出现故障时，可能会导致动脉粥样硬化、血栓形成、炎症和癌症等各种情况。因此，该方案解决了造成我们社会大多数死亡的疾病的基本问题。我们将使用被证明能够提供精确信息的技术，即负责细胞功能(或故障)的分子和生化过程。然而，在每个单独的项目中，都会有一条明确的临床使用、诊断或治疗途径。事实上，在该计划的一些组成部分中，已经有潜在的治疗和诊断方法在开发和试验中。

This program of research is firmly focussed on the basic mechanisms involved in normal functioning of cells and tissues, followed by a step by step process to understand the abnormal or the diseased. The disease states we are investigating involve the blood and blood vessels, and when there is malfunction it may contribute to conditions as diverse as atherosclerosis, thrombosis, inflammation and cancer. The program thus addresses the fundamentals of diseases which are responsible for most deaths in our society. We will use technology which is proven to provide precise information, the molecular and biochemical processes responsible for cell function (or malfunction). However in each individual project there will be a clear path to a clinical use, diagnostic or therapeutic. Indeed in a number of the components of the program there are already potential treatments and diagnostics in development and trial.