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Viral Determinants of HIV-1 Transcriptional Latency in the Central Nervous System: Impact on Cure Strategies

Viral Determinants of HIV-1 Transcriptional Latency in the Central Nervous System: Impact on Cure Strategies
中枢神经系统中 HIV-1 转录潜伏期的病毒决定因素:对治疗策略的影响
批准号:
nhmrc : 1105962
负责人:
Prof Melissa Churchill
金额:
$58.11万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 2018-12-31

项目摘要

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中文摘要
翻译
这笔拨款将确定导致HIV-1在中枢神经系统潜伏的因素,并将确定旨在逆转潜伏的药物对中枢神经系统内HIV-1和中枢神经系统细胞的影响。
英文摘要
This grant will identify the factors responsible for HIV-1 latency in the CNS, and will determine the effect of drugs aimed at reversing latency both on HIV-1 within the CNS, and also on the cells of the CNS.
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会议论文
HIV Phenotypes Important for the Establishment of Persistent Reservoirs in the Central Nervous System and which impact Neurotropism and Neuropathogenesis
  • 批准号:
    nhmrc : 1105951
  • 项目类别:
    Project Grants
  • 资助金额:
    $33.01万
  • 财政年份:
    2016
  • 负责人:
    Prof Melissa Churchill
  • 依托单位:
Viral Determinants of HIV-1 Transcriptional Latency in the Central Nervous System
Elucidating the flexibility of coreceptor engagement by HIV-1 important for macrophage tropism and escape from entry inhibitors
Histone deacetylase inhibitors and HIV latency
  • 批准号:
    nhmrc : 1009533
  • 项目类别:
    NHMRC Project Grants
  • 资助金额:
    $40.99万
  • 财政年份:
    2011
  • 负责人:
    Prof Melissa Churchill
  • 依托单位:
海外基金