A window of vulnerability: Impaired fear inhibition in adolescent rats

青春期是焦虑症易感性增加的时期。大脑在青春期经历了相当大的成熟，特别是前额叶皮质(PFC)，这是抑制恐惧的关键区域。这个项目调查了为什么青少年的恐惧抑制受到损害，并比较了促进青春期减少恐惧的治疗的神经机制。这项研究增加了有关青少年焦虑早期干预的新方法的新知识。

Adolescence is a period of increased vulnerability to anxiety disorders. The brain undergoes substantial maturation during adolescence, particularly the prefrontal cortex (PFC), a region critical for inhibiting fear. This project examines why fear inhibition is impaired in adolescents and compares the neural mechanisms mediating treatments that enhance fear reduction in adolescence. This research adds new knowledge about novel approaches for early interventions for adolescent anxiety.