A window of vulnerability: Impaired fear inhibition in adolescent rats

青春期是一个易患焦虑症的时期。大脑在青春期经历了实质性的成熟，尤其是前额叶皮层（PFC），这是一个抑制恐惧的关键区域。本项目探讨了青少年恐惧抑制受损的原因，并比较了促进青少年恐惧减少的治疗的神经机制。这项研究为早期干预青少年焦虑的新方法增加了新的知识。

Adolescence is a period of increased vulnerability to anxiety disorders. The brain undergoes substantial maturation during adolescence, particularly the prefrontal cortex (PFC), a region critical for inhibiting fear. This project examines why fear inhibition is impaired in adolescents and compares the neural mechanisms mediating treatments that enhance fear reduction in adolescence. This research adds new knowledge about novel approaches for early interventions for adolescent anxiety.