A genetic analysis of the role of an atypical hexokinase in gene regulation

非典型己糖激酶在基因调控中作用的遗传学分析。本计画探讨一个与所有生物相关的问题--细胞环境的改变如何导致基因表现的改变？本项目的目的是通过研究构巢曲霉xprF基因来研究己糖激酶在基因调控中的作用，该基因编码一种不寻常的己糖激酶。己糖激酶被认为是植物、动物和真菌中的葡萄糖传感器，并且在人类糖尿病的发展中起作用。在植物中，糖影响许多过程，包括生长、开花、光合作用、氮代谢、淀粉合成、色素沉着和对病原体的反应。

A genetic analysis of the role of an atypical hexokinase in gene regulation. This project addresses a question which is relevant to all living things-how do changes in the environment of a cell bring about a change in gene expression? The aim of this project is to investigate the role of hexokinases in gene regulation by studying the Aspergillus nidulans xprF gene, which encodes an an unusual hexokinase. Hexokinases are thought to be the glucose sensors in plants, animals and fungi, and play a role in the development of diabetes in humans. In plants, sugars affect many processes including growth, flowering, photosynthesis, nitrogen metabolism, starch synthesis, pigmentation and response to pathogens.