Structural studies on chaperone protein machines from an Antarctic archeon
Structural studies on chaperone protein machines from an Antarctic archeon
批准号:
DP120102285
负责人:
Prof Paul Curmi
金额:
$21.48万
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2015-04-30
中文摘要
该项目旨在了解两个基本的生物学过程,蛋白质折叠和RNA折叠的预防,这对所有生命都至关重要,特别是在寒冷中生存。该项目将确定蛋白质折叠机的结构,展示它是如何工作的,并确定RNA在合成后是如何被保护的。
英文摘要
This project is to understand two fundamental biological processes, protein folding and prevention of RNA folding, that are crucial to all life, in particular, to survival in the cold. The project will determine the structure of the protein folding machine, showing how it works, and determine how RNA is protected after synthesis.
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会议论文
X-ray facility for protein crystallography
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批准号:LE190100165
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项目类别:Linkage Infrastructure, Equipment and Facilities
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资助金额:$27.18万
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财政年份:2019
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负责人:Prof Paul Curmi
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依托单位:
Flick the biological quantum switch: light controls photosynthetic proteins
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批准号:DP180103964
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项目类别:Discovery Projects
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资助金额:$28.54万
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财政年份:2018
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负责人:Prof Paul Curmi
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依托单位:
Engineering an artificial protein molecular motor
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批准号:DP170103153
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项目类别:Discovery Projects
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资助金额:$26.66万
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财政年份:2017
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负责人:Prof Paul Curmi
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依托单位:
Protein structure controls light harvesting in photosynthetic light algae
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批准号:DP150102580
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项目类别:Discovery Projects
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资助金额:$25.86万
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财政年份:2015
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负责人:Prof Paul Curmi
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依托单位:
Evolution of the light harvesting system in cryptophyte algae: protein structure to quantum coherence
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批准号:DP110104725
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项目类别:Discovery Projects
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资助金额:$23.22万
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财政年份:2011
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负责人:Prof Paul Curmi
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依托单位:
Structural and pharmaceutical studies on a novel human protein, MIC-1
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批准号:LP0883838
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项目类别:Linkage Projects
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资助金额:$36.04万
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财政年份:2009
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负责人:Prof Paul Curmi
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依托单位:
Ultrahigh resolution crystallography and ultrafast laser spectroscopy to uncover the evolution and mechanisms of a unique algal light harvesting system
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批准号:DP0881251
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项目类别:Discovery Projects
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资助金额:$19.73万
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财政年份:2008
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负责人:Prof Paul Curmi
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依托单位:
X-ray crystallography resource for membrane proteins and large macromolecular complexes
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批准号:LE0882295
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项目类别:Linkage Infrastructure, Equipment and Facilities
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资助金额:$15.0万
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财政年份:2008
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负责人:Prof Paul Curmi
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依托单位:
Crystallographic studies of CLIC family proteins
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批准号:nhmrc : 350844
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项目类别:NHMRC Project Grants
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资助金额:$33.71万
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财政年份:2005
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负责人:Prof Paul Curmi
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依托单位:
Probing the control and action of CLIC1/NCC27, an unusual chloride ion channel, by x-ray crystallography
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批准号:nhmrc : 209540
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项目类别:NHMRC Project Grants
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资助金额:$18.09万
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财政年份:2002
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负责人:Prof Paul Curmi
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依托单位:
X-ray Crystal Structure of NCC27: a Novel Chloride Channel Protein from Human Macrophages
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批准号:nhmrc : 990847
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项目类别:NHMRC Project Grants
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资助金额:$15.41万
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财政年份:1999
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负责人:Prof Paul Curmi
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依托单位:
国内基金
海外基金
脂滴聚集型小胶质细胞介导的髓鞘病变促进小鼠抑郁样行为及其机制研究
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批准号:82371528
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项目类别:面上项目
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资助金额:49.00万元
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批准年份:2023
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负责人:李媛
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依托单位:
星形胶质细胞介导的髓鞘吞噬参与慢性脑低灌注白质损伤的机制研究
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批准号:82371307
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项目类别:面上项目
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资助金额:49.00万元
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批准年份:2023
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负责人:汤耀辉
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依托单位: