Motor performance and the influence of neuromuscular fatigue in knee osteoarthritis

膝关节骨性关节炎会导致慢性疼痛，限制活动能力，降低成千上万加拿大人的生活质量。这一负担因医疗费用而加重——加拿大每年用于治疗膝骨关节炎的费用超过44亿美元。在日常活动中施加在膝盖上的负荷是引发和促进膝关节关节炎的关键。然而，我们对日常活动引起的疲劳如何影响这种负荷环境知之甚少。本研究计划评估疲劳对膝关节负荷的影响。

Knee osteoarthritis causes chronic pain, limits mobility and reduces quality of life for thousands of Canadians. This burden is compounded by healthcare costs - over $4.4 billion is spent every year in Canada to manage knee osteoarthritis. The loads placed on the knee during daily activities are critical in triggering and facilitating knee arthritis. However, we know very little about how fatigue induced by daily activities contributes to this loading environment. This research program evaluates the influence of fatigue on the loads placed on the knee.