Department Core Facility Plate Reader

这是一个最先进的餐盘阅读器的需求，将满足人类健康和营养科学系的12名教员研究人员，他们的68名研究生，以及每年类似数量的本科生项目的需求。这12名教员研究人员中有5名强烈支持这一申请。12名教师研究细胞代谢的各个方面，或需要测量细胞代谢物，酶活性或信号剂，以描述和量化细胞，组织和器官中的生理或病理生理过程。这个新的车牌读取器将取代一个老化的（超过12年），越来越不可靠，并减少另一个研究人员的仪器的大量使用的负荷。虽然该部门有两台较新的（不到5年的）车牌阅读器，但它们“属于”需要专用设备的大型实验室团队的研究人员。因此，所要求的读版器是为部门研究人员提供非常高水平的服务，他们需要使用具有UV，发光，吸光度，荧光和动力学能力的好的读版器。这些设备也将被在申请人实验室工作的博士后研究员和研究生使用。这些设备在培养本科生方面也很重要，我们已经增加了许多优秀的实验室研究项目。学习如何使用这些设备和处理样品进行分析是这些人员培训的重要组成部分。

This request is for a state of the art plate reader that will serve the needs of 12 faculty researchers in the Department of Human Health and Nutritional Sciences, their 68 graduate students, and a similar number of undergraduate student projects annually. Five of these 12 faculty researchers are strongly supporting this application. The 12 faculty researchers either study various aspects of cellular metabolism, or need to measure cellular metabolites, enzyme activities or signalling agents to describe and quantify physiological or pathophysiological process in cells, tissues and organs. This new plate reader would replace an aging one (over 12 years old) that is increasingly unreliable, and reduce the load on another researcher's instrument that is heavily used. While there are two newer (less than 5 years old) plate readers in the Department, they 'belong' to researchers with large lab groups who needed dedicated equipment. The requested plate reader is therefore to provide a very good level of service to Departmental researchers needing to use a good plate reader with UV, luminescence, absorbance, fluorescence and kinetic capabilities.The equipment would also be used by post-doctoral fellows and graduate students working in the applicants' labs. This equipment is also important in the training of undergraduate students, of which we have increased numbers performing excellent, lab-based research projects. Learning how to use this equipment and processing samples for analysis comprises an important part of the training of these people.