UNC BSL3 Core Facility
北卡罗来纳大学 BSL3 核心设施
基本信息
- 批准号:10795381
- 负责人:
- 金额:$ 791.68万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2023
- 资助国家:美国
- 起止时间:2023-09-06 至 2028-05-31
- 项目状态:未结题
- 来源:
- 关键词:AnimalsCommunicable DiseasesCommunitiesContainmentCore FacilityCoronavirusDisease ProgressionEquipmentFutureGillsGoalsGrowthHealthHumanImageImmune responseInfectionInfectious Diseases ResearchInfrastructureInstitutionLaboratoriesLaboratory ResearchLearningPathogenesisPharmacy SchoolsPublic HealthReadinessResearchResearch PersonnelResearch Project GrantsSchoolsTechnologybiosafety level 3 facilitydesign and constructionfuture pandemichealth care availabilityinstrumentationmedical schoolsmicrobialnovel therapeuticsnovel vaccinespathogenic virusprogramsrecruitresponsesquare footusability
项目摘要
PROJECT SUMMARY / ABSTRACT:
The central goal of this project is to construct a 10,000 square feet biosafety level 3 (BSL3) research laboratory
core facility to promote readiness to respond to future pandemics. Infectious diseases pose a severe and
increasing threat to human health, especially in communities that lack access to health care. UNC programs will
soon exceed current infrastructure capacity due to increase demand. A strategic review of our microbial
pathogenesis and infectious disease community concluded that urgent action was essential to support the high
containment programs. Among the barriers to the growth of research was a lack of access to critical technologies
and animal space within the existing BSL3 laboratories. This transformative BSL3 core facility will allow UNC to
expand to meet current and projected research needs in the UNC School of Medicine, School of Pharmacy, and
Gillings School of Global Public Health. UNC has engaged multiple stakeholders across the research community
to design and construct a centralized BSL3 suite to characterize the immune responses to coronavirus and other
emerging viral pathogens and learn about what drives immune response, disease progression, and protection
against future infection. The proposal will attain four objectives: 1. Design and construct a high containment
facility to bring investigators working on emerging and re-emerging infections together; 2. Enable access to
specialized instrumentation including aerobiology and imaging equipment for supporting high containment
research; 3. Create institution-wide core space to allow recruitment of new investigators to the infectious disease
research community by increasing usable laboratory space in the BSL3 facility and purchasing new equipment
that will serve investigators within the many UNC centers, institutes, and departments and their nationwide
collaborators; 4. Enhance UNC's ability to lead the rapid response generating new therapeutics and vaccines to
save lives on a local, national, and even global level.
项目摘要/摘要:
该项目的中心目标是建设一个10,000平方英尺的生物安全3级(BSL3)研究实验室
促进做好应对未来大流行准备的核心设施。传染病构成了严重和
对人类健康的威胁越来越大,特别是在缺乏医疗保健的社区。北卡罗来纳大学的计划将
由于需求增加,很快就会超过目前的基础设施容量。对我们的微生物的战略回顾
致病机制和传染病社区得出结论,采取紧急行动对支持高
遏制计划。阻碍研究增长的障碍之一是缺乏关键技术
以及现有BSL3实验室内的动物空间。这一变革性的BSL3核心设施将使北卡罗来纳大学能够
扩展以满足北卡罗来纳大学医学院、药学院和
吉林斯全球公共卫生学院。北卡罗来纳大学与整个研究社区的多个利益相关者进行了接触
设计和构建一套集中的BSL3套件,以表征对冠状病毒和其他
新出现的病毒病原体,并了解驱动免疫反应、疾病进展和保护的因素
预防未来的感染。该提案将实现四个目标:1.设计和建造高安全壳
将致力于研究新发和再次出现的感染的调查人员聚集在一起的设施;2.允许访问
支持高密封性的专门仪器,包括空气生物学和成像设备
研究;3.创建机构范围的核心空间,以便招募新的传染病研究人员
通过增加BSL3设施中的可用实验室空间和购买新设备来研究社区
这将为北卡罗来纳大学的许多中心、研究所和部门及其全国范围内的调查人员提供服务
合作者;4.增强北卡罗来纳大学领导快速反应产生新疗法和疫苗的能力
在地方、国家甚至全球层面上拯救生命。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Craig A Fletcher其他文献
Craig A Fletcher的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Craig A Fletcher', 18)}}的其他基金
Steam Sterilizer for the McGavran-Greenberg Animal Facility at UNC Chapel Hill
北卡罗来纳大学教堂山分校麦加夫兰-格林伯格动物设施的蒸汽灭菌器
- 批准号:
8902300 - 财政年份:2015
- 资助金额:
$ 791.68万 - 项目类别:
Renovation for Animal Facility Safety & Long-Tern Support of Research at the Univ
动物设施安全改造
- 批准号:
8713008 - 财政年份:2014
- 资助金额:
$ 791.68万 - 项目类别:
Research Education Program for Laboratory Animal Medicine Veterinarians
实验动物医学兽医研究教育计划
- 批准号:
9093870 - 财政年份:2013
- 资助金额:
$ 791.68万 - 项目类别:
相似海外基金
Develop a programme to support the prevention of Non-Communicable Diseases (NCDs) in the Republic of Kenya.
制定一项计划,支持肯尼亚共和国预防非传染性疾病 (NCD)。
- 批准号:
23K09892 - 财政年份:2023
- 资助金额:
$ 791.68万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Research Training in Global Non-Communicable Diseases
全球非传染性疾病研究培训
- 批准号:
10554719 - 财政年份:2023
- 资助金额:
$ 791.68万 - 项目类别:
Usefulness of metabolite biomarker as a common pathway for the prevention of non-communicable diseases and frailty
代谢生物标志物作为预防非传染性疾病和虚弱的常见途径的有用性
- 批准号:
23H00452 - 财政年份:2023
- 资助金额:
$ 791.68万 - 项目类别:
Grant-in-Aid for Scientific Research (A)
Strengthening Research Capacity in Innovative Global Health Technologies for Non-Communicable Diseases in Uganda
加强乌干达非传染性疾病创新全球卫生技术的研究能力
- 批准号:
10469877 - 财政年份:2022
- 资助金额:
$ 791.68万 - 项目类别:
Building capacity for Implementation Science research in Non-Communicable Diseases (BImS-NCDs)
非传染性疾病(BImS-NCD)实施科学研究的能力建设
- 批准号:
10469788 - 财政年份:2022
- 资助金额:
$ 791.68万 - 项目类别:
Building capacity for Implementation Science research in Non-Communicable Diseases (BImS-NCDs)
非传染性疾病(BImS-NCD)实施科学研究的能力建设
- 批准号:
10594552 - 财政年份:2022
- 资助金额:
$ 791.68万 - 项目类别:
Occupational disparities in survival from cancer and non-communicable diseases
癌症和非传染性疾病生存率的职业差异
- 批准号:
22K17401 - 财政年份:2022
- 资助金额:
$ 791.68万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
"Increasing take-up of preventative health behaviours to mitigate the rise of non-communicable diseases in lower- and middle- income countries: a comp
“在低收入和中等收入国家中,更多地采用预防性健康行为来减缓非传染性疾病的增加:一项比较
- 批准号:
2751288 - 财政年份:2022
- 资助金额:
$ 791.68万 - 项目类别:
Studentship
Development of a comprehensive self-care system utilizing big data/AI to cure non-communicable diseases and validation of its effectiveness
开发利用大数据/人工智能治疗非传染性疾病的综合自我护理系统并验证其有效性
- 批准号:
22H03529 - 财政年份:2022
- 资助金额:
$ 791.68万 - 项目类别:
Grant-in-Aid for Scientific Research (B)














{{item.name}}会员




