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Role of Early Childhood Maltreatment and Glucocorticoid Receptor Modulator Gene (FKBP5) in Sensitizing the Biological Stress Response System in Depressed and Non-Depressed Adolescents

Role of Early Childhood Maltreatment and Glucocorticoid Receptor Modulator Gene (FKBP5) in Sensitizing the Biological Stress Response System in Depressed and Non-Depressed Adolescents
早期儿童虐待和糖皮质激素受体调节基因 (FKBP5) 在抑郁和非抑郁青少年生物应激反应系统敏感中的作用
批准号：
253285
负责人：
Mazurka Raegan
金额：
$1.27万
依托单位：
Queen's University (Kingston, Ontario)
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2012
资助国家：
加拿大
项目状态：
已结题
起止时间：
2012-02-01 至 2013-02-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=253285&lang=en
关键词：
Adolescence Childhood Maltreatment Cortisol Depression Fkbp5 Gene Gene-Environment Interaction Glucocorticoids Hpa Axis Reactivity Stress Sensitization Trier Social Stress Test

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中文摘要
翻译
抑郁症是一种使人衰弱和反复发作的疾病，大约11%的加拿大人在他们生命的某个阶段受到影响。许多人在青少年时期就经历了第一次抑郁。因此，对这一年龄组的研究尤为重要
英文摘要
Depression is a debilitating and recurrent illness that affects approximately 11% of Canadians at some point in their lives. Many people experience their first episode of depression as adolescents. Thus, the study of this age group is particularly importa
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会议论文
Harnessing Health Systems Data to Optimize Outcomes for Depression in Nova Scotia
Emotion Regulation as a Behavioural Mechanism to Account for the Differential Effect of Childhood Maltreatment on Biological Stress Reactivity in Depressed versus Non-Depressed Adolescents
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