Electrodeposited copper coatings for biomedical applications

拟议的Engage赠款申请的直接目标是开发新的铜涂层，通过赋予现有生物材料管理最终决定生物医学植入物生物结果的细胞事件的能力来推动现有生物材料的发展。特别是，我们建议评估由工业合作伙伴Integran Technologies Inc.提供的各种电沉积铜涂层的细胞毒性和生物性能。此外，通过利用基于纳米技术的方法，我们计划同时为这些铜涂层提供增强的生物性能和更好的耐腐蚀性。这一探索性项目的结果将验证铜涂层作为改善生物材料集成的一种有价值的替代策略的潜力。

The immediate objective of the proposed Engage grant application is to develop novel copper coatings to advance current biomaterials by endowing them with the ability to managing the cellular events that ultimately determine the biological outcome of biomedical implants. In particular, we propose to assess the cytotoxicity and the biological properties of various electrodeposited copper coatings provided by the industrial partner, Integran Technologies Inc. In addition, by exploiting nanotechnology-based approaches we plan on simultaneously providing these copper coatings with enhanced biological properties and a better corrosion resistance. Results from this exploratory project will validate the potential of copper coatings as a valuable alternative strategy to improve the integration of biomaterials.