In vitro activity of water-jet modified titanium

水射流改性钛的体外活性

• 批准号: 486769-2015
• 负责人: Variola, Fabio
• 金额: $ 1.82万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Engage Grants Program
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=585777
• 关键词: vitro; activity; water; jet; modified

The immediate objective of the proposed Engage grant application is to investigate the cellular response to water-jet modified titanium samples. In particular, it is proposed to carry out in vitro assays with osteoblastic and fibroblastic cells to assess the biological properties of titanium samples modified by pulsed water-jet, a proprietary technique developed by the industrial partner, VLN Advanced Technologies Inc. Results from this exploratory project will validate the potential of pulsed water jet as a valuable alternative to grit blasting for the surface modification of medically relevant metals for applications in implantology.

Engage资助申请的直接目标是研究细胞对水射流改性钛样品的反应。特别是，它建议进行成骨细胞和成纤维细胞的体外试验，以评估由脉冲水射流，由工业合作伙伴，VLN先进技术公司开发的专有技术改性的钛样品的生物学特性。该探索性项目的结果将验证脉冲水射流作为喷砂处理的有价值替代方法的潜力，用于植入学应用中的医学相关金属的表面改性。