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Cell Production Augmentation Techniques

Cell Production Augmentation Techniques
细胞产量增强技术
批准号:
463108-2014
负责人:
McEachern, Cam
金额:
$1.82万
依托单位:
依托单位国家:
加拿大
项目类别:
Applied Research and Development Grants - Level 1
财政年份:
2014
资助国家:
加拿大
项目状态:
已结题
起止时间:
2014-01-01 至 2015-12-31

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中文摘要
翻译
再生医学涉及基于细胞的植入物的移植,对提高常规治疗的临床疗效有很大的希望。这是可能的,因为植入修复特异性细胞(如干细胞)具有恢复组织正常功能的能力。目前制造基于细胞的产品的程序本质上都是手动的,因此不能实现高可重复性和成本效益。自动化生产可以通过机器人复制人工操作来实现;然而,普遍的行业挑战是,现有的基本细胞培养机器人系统非常复杂,需要大量的操作空间,并且需要高资本设备投资。Octane biotechnologies面临的挑战是开发一种创新的,具有成本效益的自动化生物反应器系统,以满足临床生产的挑战。
英文摘要
Regenerative medicine involving the transplantation of cell-based implants holds great promise for improving the clinical efficacy of conventional treatments. This is possible because the implantation of repair-specific cells (such as stem cells) have the ability to restore tissue to normal function. The current procedures to create cell-based products are all manual in nature and hence do not enable high reproducibility and cost-effectiveness. Automated production could potentially be achieved through the robotic duplication of manual actions; however, the general industry challenge is that existing robotic systems for basic cell culture are highly complex, require significant space for operation, and require a high capital equipment investment. Octane Biotechs challenge is to develop an innovative, cost-effective and automated bioreactor-based system to meet the clinical production challenges.
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