Development of sensors for mycotoxins

食品和饲料中毒素的不安全水平需要新的技术来检测这些化合物沿着从生产到消费的食品连续体。虽然传统的分析技术存在，但仍然存在对更简单、更快速和具有成本效益的食品安全测试方法的真实的需求。生物传感器由靶向感兴趣的分析物的特异性分子识别探针和将该识别事件转化为可测量信号的手段组成。由于分子识别是生物传感的基础，因此开发用于食品安全监测的新型分子识别探针越来越受到关注。由于它们的体外选择和生产，相对较新的适体技术正在成为用于生物传感器平台的可行替代方案。该提案审查了食品安全相关靶标的适体的开发，以期开发生物传感器平台，其中这些探针可以

Unsafe levels of toxins in food and feed requires new technology for the detection of these compounds along the food continuum from production to consumption. While traditional analytical techniques exist, there is still a real need for simpler, more rapid, and cost-effective approaches to food safety testing. Biosensors consist of a specific molecular recognition probe targeting an analyte of interest and a means of converting that recognition event into a measurable signal. As molecular recognition is the foundation of biosensing, there has been increased focus on the development of new molecular recognition probes for food-safety monitoring . Because of their in vitro selection and production, the relatively new technology of aptamers is emerging as a viable alternative for use in biosensor platforms. This proposal examines the development of aptamers for food safety related targets with a view to developing biosensor platforms in which these probes can be