Minimally-invasive, wireless, multimodal micro-optrodes for brain sensing

拟议的为期3年的研究项目涉及光纤、无线技术和 神经学科学对大脑活动的研究。该项目旨在结合物理学的互补专业知识， 神经生物学和电气工程三个领先的研究实验室共同开发一种新型的微创、无线 多模式脑微探针技术，将最大限度地增加大脑活动量，神经化学，细胞信号和 从自由行为的动物身上获得的高时间分辨率的离子波动，同时显著减小了大小 植入物的。该项目涉及自然科学和健康科学方面的经验丰富的研究人员，以及加拿大的一项技术 用户组织。 该项目将加速对阿尔茨海默氏症和老年痴呆症等脑部疾病的新疗法的开创性研究。 帕金森氏病、癫痫、抑郁症、强迫症和慢性疼痛，主要由年龄相关驱动 通过减少临床前研究的成本和时间，老龄化人口中的神经疾病

The proposed 3-year research project relates to the rapid convergence of Fiber optics, Wireless technology, and Neurological sciences to the study of brain activity. The project aims to combine the complementary expertise of physics, neurobiology, and electrical engineering of three leading research labs to develop a novel minimally-invasive, wireless, multimodal brain microprobe technology that will maximize the amount of brain activity, neurochemistry, cell signaling and ionic fluctuations acquired, with high temporal resolution, from freely behaving animals while minimizing significantly the size of the implant. The project involves experienced researchers in natural and health sciences, and a Canadian technology user organization. The project will accelerate ground breaking research towards new treatments for brain diseases like Alzheimers and Parkinsons disease, epilepsy, depression, obsessive-compulsive disorders and, chronic pain,driven mainly by age-related neurological disorders in an ageing population, by decreasing the cost and time of preclinical studies