Assessment of pMDI spray characterization using cascade impactors and laser techniques

加压计量吸入器（pMDI）或“膨化器”、干粉吸入器（DPI）和雾化器通常用于治疗肺部疾病。肺协会的统计数据表明，高达约10%的人口可能患有呼吸系统疾病，需要在他们的生活中接受治疗。文献中的大多数气溶胶特性描述都是从级联撞击器中获得最终的粒度分布。CoralTec公司（多伦多，ON）正在研究通过将其设备与传统级联撞击器相结合，使用过渡方法扩展和调整其D30喷雾液滴粒度分析仪技术以测量药物气溶胶（吸入器产生的直径约为3.5微米的药物液滴）的可能性。

Pressurized metered-dose inhalers (pMDIs) or "puffers", dry powder inhalers (DPIs), and nebulizers are normally used in the treatment of lung diseases. Statistics from Lung Associations indicate that up to approximately 10% of the population may suffer from respiratory illnesses requiring treatment in part of their lives. Most of the aerosol characterization available in the literature consists in obtaining the final particle size distribution from cascade impactors. CoralTec Inc. (Toronto, ON) is investigating the possibility of expanding and adapting their D30 spray droplet sizer technology towards the measurement of pharmaceutical aerosols (medication droplets with diameters around 3.5 microns produced from inhalers) using a transitional approach by combining their device with traditional cascade impactors.