Microfluidic mechanical stimulation bioreactor

机械力使体内的组织和细胞伸展，这是它们正常功能的一部分。事实上，有些人 机械拉伸的程度是维持健康组织所必需的，而过度拉伸可能会导致损伤或 会导致疾病。拉伸对组织和细胞功能、损伤和疾病的影响经常在 实验室通过在细胞拉伸系统中的可变形膜上培养细胞。 与提供交钥匙生物材料测试的加拿大公司CellScale Biomaterals Testing合作 为医学研究人员和科学家提供解决方案，我们将开发一种微流控系统，使 研究人员研究细胞对不同程度拉伸的反应。向微尺度的转变将 通过最大限度地减少试剂消耗，显著提高实验效率并降低运行成本。 这项研究将有助于理解细胞在疾病反应和组织中的作用机制。 再生。 由此产生的系统将由CellScale向再生医学、生物医学 科学和医疗设备在加拿大和世界各地。

Mechanical forces cause tissues and cells in the body to stretch as part of their normal function. In fact, some degree of mechanical stretch is required to maintain healthy tissues, while overstretching can cause damage or lead to disease. The effects of stretch on tissue and cell function, damage, and disease are often studied in laboratories by growing cells on deformable membranes in cell stretching systems. In partnership with CellScale Biomaterials Testing, a Canadian company that provides turn-key biomaterial test solutions to medical researchers and scientists, we will develop a microfluidic system that will allow researchers to study the response of cells to varying levels of stretching. The move towards the microscale will significantly improve experiment efficiencies and lower operational costs by minimizing reagent consumption. This research will help to understand the mechanisms of cell function in disease response and tissue regeneration. The resulting system will be marketed by CellScale to researchers in regenerative medicine, biomedical science, and medical devices in Canada and worldwide.