Aptamer-based smart materials for biosensing and delivery applications

“智能”材料是一类新兴的多功能材料，其物理或化学性质可根据外部刺激而可控地改变。通过结合先进材料的特性和适应环境变化的能力，这些材料在传感和药物输送方面得到了应用。虽然许多智能材料对物理或化学刺激(pH、温度)做出反应，但开发对特定分子或生物分子敏感的智能材料是一个越来越感兴趣的话题。这些系统的制备涉及能够识别目标分子的组件(分子识别探针)的整合。适体是一种分子识别探针，具有许多独特的性质，使其非常适合于新型智能材料系统。

“Smart” materials are an emerging class of multifunctional materials whose physical or chemical properties are controllably altered in response to an external stimulus. By combining the properties of an advanced material with the ability to adapt in response to a change in their environment, these materials are finding applications in sensing and drug delivery. While many smart materials respond to physical or chemical stimuli (pH, temperature), the development of smart materials that are sensitive to specific molecules or biomolecules is a topic of growing interest. Preparation of these systems involves the integration of a component that can recognize the target molecule (molecular recognition probe).  Aptamers are molecular recognition probes that have many unique properties that make them well-suited to novel smart material systems.