Strategies for AC electrokinetic manipulation and detection of viruses in microfluidic environments

目前的诊断工具无法提供病原体病毒(艾滋病毒-艾滋病、甲型H1N1流感、西尼罗河病毒)的早期检测，因此无法预防或早期遏制感染。此外，世界各地的政府以及平民和军方越来越担心生物战和生物恐怖主义袭击的威胁。不幸的是，对致病颗粒的检测需要耗时和费力的程序，这些程序通常必须在配备适当的中央设施中进行。这会导致诊断延误、医疗成本上升、工作效率下降，最重要的是，还会导致可预防的死亡。然而，设备小型化的研究带来了希望，即微型传感器，如今天用于血糖监测的微型传感器，有朝一日将能够在“便携式实验室”实现对病毒的现场检测。

The inability of present-day diagnostic tools to provide early detection of pathogenic viruses (HIV-AIDS, H1N1, West Nile) does not allow prevention or early containment of an infection. Additionally, governments around the world, along with civilians and the military, are becoming increasingly concerned with threats of biological warfare and bio-terrorism attacks. Unfortunately, testing for pathogenic particles requires time-consuming and laborious procedures that usually must be performed in properly equipped, centralized facilities. This translates into delayed diagnoses, higher health care costs, lost of work productivity and, most importantly, preventable fatalities. Research in device miniaturization, however, has generated hope that micro-sensors, such as those used today for blood glucose monitoring, will one day enable on-site detection of viruses in "portable laboratories".