Phytoglycogen nanoparticles as a technology platform for engineered anti-infective agents

PhytoSpherixTM纳米颗粒是一种无毒、可生物降解的专利生物材料，由Mirexus Inc.(Guelph，On)从安大略省种植的甜玉米中生产。每个纳米颗粒由一个高度支化的葡萄糖均聚物分子组成，提供了一个统一的表面物理化学，活性成分可以与之偶联。PhytoSpherixTM特别适用于营养食品、化妆品、药品和生物医学应用的广泛应用。它可以通过添加官能团或各种活性药物成分(如抗生素)进行修饰。最后一个特征是切合实际的：在过去的几十年里，很少有新的抗生素进入市场，这是一个全球公认的问题。

PhytoSpherixTM nanoparticles are a nontoxic, biodegradable proprietary biomaterial generated by Mirexus Inc. (Guelph, ON) from Ontario-grown sweet corn. Each nanoparticle consists of a single molecule of highly-branched glucose homopolymer, providing a uniform surface physico-chemistry to which active ingredients can be conjugated. PhytoSpherixTM is especially suited for use in a wide range of applications for nutraceuticals, cosmetics, pharmaceuticals and biomedical applications. It can be modified by adding functional groups or various active pharmaceutical ingredients e.g. antibiotics. This last feature is pertinent: over the last decades few new antibiotics have entered the market, which is a globally-recognised concern.