Development of a physiological cardiac microtissue platform for drug development
Development of a physiological cardiac microtissue platform for drug development
批准号:
361190
负责人:
Simmons Craig A
金额:
$31.09万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-10-01 至 2019-10-01
中文摘要
药物对心脏的不良疗效和不可预测的毒性作用是导致药物下架的主要原因。许多药物在患者身上的作用是不可预测的,因为它们是在实验室里使用塑料培养皿中培养的细胞进行测试的,在动物身上也是如此。
英文摘要
Poor efficacy and unpredictable toxic effects of drugs on the heart are leading causes of removal of a drug from the market. Many drugs act unpredictably in patients because they are tested in labs using cells grown in plastic dishes and in animals that p
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