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Comparative effects of a D2 and mixed D1-D2 dopamine antagonist on gambling and amphetamine reinforcement in pathological gamblers and healthy controls

Comparative effects of a D2 and mixed D1-D2 dopamine antagonist on gambling and amphetamine reinforcement in pathological gamblers and healthy controls
D2 和混合 D1-D2 多巴胺拮抗剂对病态赌徒和健康对照者赌博和安非他明强化的比较影响
批准号：
179695
负责人：
Zack Martin H
金额：
$30.09万
依托单位：
Centre for Addiction and Mental Health (Toronto)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2009
资助国家：
加拿大
项目状态：
已结题
起止时间：
2009-03-01 至 2012-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=179695&lang=en
关键词：
Amphetamine D1 And D2 Receptors Dopamine Antagonists Pathological Gambling Priming Reinforcement

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中文摘要
翻译
病态赌博是一种严重的疾病，折磨着2-3%的加拿大人。目前还没有药物被批准用于治疗这种疾病。更好地了解病理性赌博的神经化学可以为药物开发提供信息。证据显示
英文摘要
Pathological gambling is a serious disorder that afflicts 2-3% of Canadians. There are currently no medications approved to treat it. Better understanding of the neurochemistry of pathological gambling could inform medication development. Evidence suggest
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会议论文
Probing the role of dopamine in co-morbid pathological gambling and Parkinson's disease: Behavioural pharmacology, electrophysiology, neuroimaging, and genetics.
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