The Influence of Parental Experience On Brain Development, Behaviour, and Neuroplasticity

行为神经科学的一个基本问题与成年后大脑如何发展产生我们复杂的运动、社交和认知能力有关。现在很清楚的是，大脑的发育并不是按照一个蓝图来的，相反，新生的大脑是由孕前、产前和产后的经历塑造出来的，从而产生了一个能做不可思议事情的大脑。但并非所有人的大脑都是一样的，从聪明到不太理想的结果，存在着显著的差异。在证明了不同时期的积极和消极经历都会影响大脑和行为发育之后，我建议系统地检查这些经历在几个发育时间点的影响，包括孕前（孕前和孕后）、妊娠期（孕后）、围产期和青春期。

One of the fundamental questions in behavioural neuroscience relates to how the brain develops to produce our complex motor, social, and cognitive abilities in adulthood. It is now clear that brain development does not follow a blueprint but rather the nascent brain is sculpted by preconception, prenatal, and postnatal experiences to produce a brain that can do marvelous things. But not all brains are the same and there is remarkable variability ranging from brilliance to less than optimal outcomes.Having demonstrated that both positive and negative experiences at different times can influence brain and behavioral development, I propose to systematically examine the effects of such experiences at several developmental time points including preconception (both sires and dams), gestational (dams), perinatal, and adolescence.