Chemical Synthesis and Applications of Oligonucleotide Analogues
Chemical Synthesis and Applications of Oligonucleotide Analogues
批准号:
RGPIN-2017-05389
负责人:
Hudson, Robert
金额:
$3.28万
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-01-01 至 2018-12-31
中文摘要
我的研究计划是关于结构修饰的寡核苷酸的发展(DNA和RNA)和非天然寡核苷酸模拟物如肽核酸(PNA和PMO):(1)扩大我们对核酸的化学,功能和生物学的理解;(2)将作为其他研究领域的序列探针和生物分子工具;和(3)可以作为基因表达的人工调节剂。另一个研究领域致力于磁共振(MR)和正电子发射断层扫描(PET)医学成像造影剂的设计,合成,理解和应用。
英文摘要
My research program is concerned with the development of structurally modified oligonucleotides (DNA and RNA) and non-natural oligonucleotide mimics such as peptide nucleic acid (PNA and PMO) that: (1) expand our understanding of the chemistry, function and biology of nucleic acids; (2) will serve as sequence probes and biomolecular tools for other areas of study; and (3) may act as artificial regulators of gene expression. Another area of research is dedicated to the design, synthesis, understanding and application of contrast agents for medical imaging by magnetic resonance (MR) and positron emission tomography (PET).
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Critical Use UVvis Spectrophotometer
-
批准号:RTI-2023-00154
-
项目类别:Research Tools and Instruments
-
资助金额:$3.93万
-
财政年份:2022
-
负责人:Hudson, Robert
-
依托单位:
Chemical Synthesis and Applications of Oligonucleotide Analogues
-
批准号:RGPIN-2017-05389
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$6.56万
-
财政年份:2021
-
负责人:Hudson, Robert
-
依托单位:
Chemical Synthesis and Applications of Oligonucleotide Analogues
-
批准号:RGPIN-2017-05389
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$3.28万
-
财政年份:2020
-
负责人:Hudson, Robert
-
依托单位:
Chemical Synthesis and Applications of Oligonucleotide Analogues
-
批准号:RGPIN-2017-05389
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$3.28万
-
财政年份:2019
-
负责人:Hudson, Robert
-
依托单位:
Chemical Synthesis and Applications of Oligonucleotide Analogues
-
批准号:RGPIN-2017-05389
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$3.28万
-
财政年份:2018
-
负责人:Hudson, Robert
-
依托单位:
Urgent Replacement of Oligonucleotide Synthesizer
-
批准号:RTI-2018-00844
-
项目类别:Research Tools and Instruments
-
资助金额:$8.07万
-
财政年份:2017
-
负责人:Hudson, Robert
-
依托单位:
Chemical Synthesis and Applications of Oligonucleotides and Analogs
-
批准号:203210-2012
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$5.1万
-
财政年份:2016
-
负责人:Hudson, Robert
-
依托单位:
Chemical Synthesis and Applications of Oligonucleotides and Analogs
-
批准号:203210-2012
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$5.1万
-
财政年份:2015
-
负责人:Hudson, Robert
-
依托单位:
Chemical Synthesis and Applications of Oligonucleotides and Analogs
-
批准号:203210-2012
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$5.1万
-
财政年份:2014
-
负责人:Hudson, Robert
-
依托单位:
Chemical Synthesis and Applications of Oligonucleotides and Analogs
-
批准号:203210-2012
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$5.1万
-
财政年份:2013
-
负责人:Hudson, Robert
-
依托单位:
Microwave Assisted Chemistry: Small molecule and Peptide Synthesis
-
批准号:439850-2013
-
项目类别:Research Tools and Instruments - Category 1 (<$150,000)
-
资助金额:$4.23万
-
财政年份:2012
-
负责人:Hudson, Robert
-
依托单位:
Chemical Synthesis and Applications of Oligonucleotides and Analogs
-
批准号:203210-2012
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$5.1万
-
财政年份:2012
-
负责人:Hudson, Robert
-
依托单位:
Synthesis, properties and applications of aligonucleotides and analogs
-
批准号:203210-2007
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.91万
-
财政年份:2011
-
负责人:Hudson, Robert
-
依托单位:
Synthesis, properties and applications of aligonucleotides and analogs
-
批准号:203210-2007
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.91万
-
财政年份:2010
-
负责人:Hudson, Robert
-
依托单位:
Synthesis, properties and applications of aligonucleotides and analogs
-
批准号:203210-2007
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.91万
-
财政年份:2009
-
负责人:Hudson, Robert
-
依托单位:
Synthesis, properties and applications of aligonucleotides and analogs
-
批准号:203210-2007
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.91万
-
财政年份:2008
-
负责人:Hudson, Robert
-
依托单位:
CD spectrophotometer
-
批准号:359757-2008
-
项目类别:Research Tools and Instruments - Category 1 (<$150,000)
-
资助金额:$8.49万
-
财政年份:2007
-
负责人:Hudson, Robert
-
依托单位:
Synthesis, properties and applications of aligonucleotides and analogs
-
批准号:203210-2007
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.91万
-
财政年份:2007
-
负责人:Hudson, Robert
-
依托单位:
Modified peptide nucleic acids and other oligonucleotide
-
批准号:203210-2002
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$3.68万
-
财政年份:2006
-
负责人:Hudson, Robert
-
依托单位:
Precision ranching
-
批准号:257585-2002
-
项目类别:Strategic Projects - Group
-
资助金额:$6.89万
-
财政年份:2006
-
负责人:Hudson, Robert
-
依托单位:
国内基金
海外基金
新型滤波器综合技术-直接综合技术(Direct synthesis Technique)的研究及应用
-
批准号:61671111
-
项目类别:面上项目
-
资助金额:58.0万元
-
批准年份:2016
-
负责人:肖飞
-
依托单位: