Contribution to neuroinflammation of immunometabolic reprogramming of resident microglia and infiltrating macrophages
Contribution to neuroinflammation of immunometabolic reprogramming of resident microglia and infiltrating macrophages
批准号:
376093
负责人:
Auger Jean-Philippe
金额:
$10.93万
依托单位国家:
加拿大
项目类别:
Fellowship Programs
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-11-01 至 2020-11-01
中文摘要
巨噬细胞是一种驻留在组织中的细胞,具有体内平衡功能,特别是在中枢神经系统中。攻击后,它们被激活并分泌介质,导致局部炎症(神经炎症)。此外,大量的
英文摘要
Macrophages are tissue-resident cells that fulfill homeostatic functions, notably in the central nervous system. Following assault, they become activated and secrete mediators that lead to a local inflammation (neuroinflammation). Moreover, large numbers
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