Pharmaceutical Technology: Controlled Drug Delivery Systems

三年前，位于蒙特利尔西岛的约翰雅培学院启动了一个与制药生产技术相关的新职业计划，以及一个新的部门。两年来，Khalid博士一直非常积极地在学院进行应用研究，我们的9名学生经常参与其中。他亦积极与本地及区域的制药公司建立沟通渠道，以确定他们的应用研究需求如何符合本署的使命、抱负和专业知识。约翰雅培学院（主要参与者Dr Khalid）希望将此申请提交给学院和社区创新计划-入门级创新促进补助金。这种类型的财政支持将使我们能够建立我们的研究能力，以便与当地行业（如Altus Formulation， Importfab和Sobio Pharmaceuticals）合作开展特定的应用研究项目。这三个项目中建议的技术平台将通过提供一系列令人印象深刻的设备以及药物配方方面的专门知识来满足这一需求。该项目的项目选择考虑了技术转让的可行性。这三个项目是：1；新型对乙酰氨基酚2分段控释制剂的研制与验证。用于难水溶性药物（BCSⅱ类）控释的聚合物基微胶囊的喷雾干燥配方及味掩蔽装置3。界面交联聚合物微胶囊的配方开发

Three years ago, John Abbott College, located in the Montreal West Island launched a new career program related to Pharmaceutical Production Technology, as well as a new department. Since two years, Dr Khalid has been very active in performing applied research at the College, where 9 of our students were regularly involved. He has also been very active in establishing communication channels with local and regional pharmaceutical companies in order to identify how their applied research needs could fit with our departmental mission, ambitions and expertise.John Abbott College (main participant Dr Khalid) would like to submit this application to the College and Community Innovation Program - Entry-Level Innovation Enhancement Grant. This type of financial support will enable us to build our research capacity in order to perform specific applied research projects in collaboration with local industries such Altus Formulation, Importfab, and Sobio Pharmaceuticals. The technology platform suggested in the three projects will respond to this need by providing access to an impressive range of equipment as well as specialized expertise in drug formulation. The choice of projects for this application was done considering the technology transfer feasibility. The three projects are:1. Development and Validation of a Novel Sectable Controlled Release Formulation of Acetaminophen2. Formulation of polymer based microcapsules using spray drying for controlled release of poorly water soluble drugs (BCS class II) and as taste masking device3. Formulation development of polymeric microcapsules using interfacial cross-linking