Preparation, isolation, and characterization of fragile acid-base complexes including intermediates of potential biological relevance

二氧化碳和硫氧化物等小活性气体的化学行为对全球变暖和酸雨的大范围影响很重要。经常被忽视的是它们在材料和生物系统中的作用。为了更多地了解这种化学，我们正在系统地探索这些气体小分子在各种环境中的反应性，包括不寻常的溶剂和多孔材料中的反应性。这种探索可以通过配位化学的使用来指导，配位化学是一种小分子或离子向反应气体提供电子的过程。当发生相互作用时，会形成新的键，这通常会导致母气的行为和反应性发生重大变化。在强相互作用的情况下，产物分子可以隔离气体。在弱相互作用的情况下，气体分子的化学可能会改变，但气体随后会被释放，因为它只被微弱地持有。*在这个提案中，我们概述了我们在各种化学环境中探索二氧化碳、二硫化碳、二氧化硫和三氧化硫的化学的计划。如上所述，这种化学对于我们大规模地理解这些工业气体将是重要的。在新的和不寻常的介质中的研究将为自然界如何处理这些重要分子提供有价值的见解，例如，在酶的活性部位，即在更小的规模上。

The chemical behavior of small reactive gases such as carbon dioxide and the sulfur oxides is important on the large-scale vis-à-vis global warming and acid rain. Often overlooked is their role in materials and in biological systems. In order to understand more of this chemistry, we are systematically exploring the reactivity of these small gaseous molecules in a wide variety of environments, including unusual solvents and also within porous materials. This exploration can be guided by the use of coordination chemistry, a process wherein a small molecule or ion donates electrons to the reactive gas. When an interaction occurs a new bond is formed, which often results in significant modification of the behavior and reactivity of the parent gas. In the case of strong interactions, the product molecules can sequester the gas. In the case of weak interactions, the chemistry of the gaseous molecule may be altered but the gas can subsequently be released because it is only weakly held.***In this proposal we outline our plan to explore the chemistry of carbon dioxide, carbon disulfide, sulfur dioxide and sulfur trioxide in a wide variety of chemical environments. As mentioned above, this chemistry will be important for our understanding of these industrial gases on a large-scale. The studies in new and unusual media will provide valuable insight as to how nature handles these important molecules within, for example, the active sites of enzymes, i.e., on a much smaller scale.************ **