Synthesis and Characterization of Non-Ionic Surfactants Prepared from Furan-2-Methanol Derivatives**

这项建议涉及一系列非离子表面活性剂的制备和性能评价，该系列非离子表面活性剂由Origin Material公司提供，其一般结构为R-F-MeOH，其中R-基团含有烷基，F和MeOH分别代表呋喃和甲醇。这些烷基化呋喃衍生物的前体可以通过Origin材料公司开发的创新催化工艺从硬纸板或木屑中大规模生产。利用R-F-MeOH衍生物作为前驱体合成非离子表面活性剂的能力将为这些生物衍生原料带来新的应用。为了实现这一目标，R-F-MeOH的甲醇取代基将被去质子化，作为环氧乙烷阴离子聚合的引发剂，并生长出亲水性的低聚(环氧乙烷)(OEO)链段。为了控制呋喃基非离子表面活性剂的亲水亲油平衡，我们将通过系统地改变R-基烷基和OEO链的长度来制备呋喃类非离子表面活性剂。每种表面活性剂都将通过稳态和时间分辨荧光**光谱进行表征，以确定其临界胶束浓度(CMC，形成胶束的表面活性剂浓度)和聚集数(NAG，每个胶束中表面活性剂分子的数量)。结合表面张力测量，这些结果将允许评估这些新型表面活性剂的有效性。将建立CMC、NAG和表面张力降低与这些表面活性剂的HLB值之间的结构-性质关系。**

This proposal concerns the preparation and properties evaluation of a series of non-ionic surfactants synthesized from derivatives of chloromethylfurfural that will be supplied by Origin Materials and have the general structure R-F-MeOH, where the R-group contains an alkyl chain and F and MeOH stand for furan and methanol, respectively. The precursors for these alkylated furan derivatives can be produced on a large scale from cardboard or wood chips via an innovative catalytic process developed by Origin Materials. The ability to use R-F-MeOH derivatives as precursors to synthesize non-ionic surfactants would lead to new applications for these bio-derived feedstocks. To achieve this, the methanol substituent of R-F-MeOH will be deprotonated to serve as initiator for the anionic polymerization of ethylene oxide and grow a hydrophilic oligo(ethylene oxide) (OEO) segment. Furan-based non-ionic surfactants (fbnios) will be prepared with systematic variations in the length of the alkyl chain in the R-group and of the OEO chain, so as to control their hydrophilic-lipophilic balance (HLB). Each surfactant will be characterized by steady-state and time-resolved fluorescence**spectroscopy to determine its critical micelle concentration (CMC, the surfactant concentration above which micelles are formed) and aggregation number (Nagg, the number of surfactant molecules per micelle). In combination with surface tension measurements, these results will allow the evaluation of the effectiveness of these novel surfactants. Structure-property relationships will be established relating the CMC, Nagg, and surface tension reduction with the HLB of these surfactants.**