Surface modification in additive manufacturing

开发具有成功骨整合的定制种植体对于安大略省的牙科，颌面和骨科护理非常重要。Liburdi拥有独特的基于直接能量沉积（DED）的增材制造（AM）或3D打印技术，该技术可以进一步开发，以有效地根据需求生产高度定制/个性化的植入物。**虽然金属植入物在牙科和关节置换手术中已经很常见，但10-15%的骨科植入物和2%的与骨结合的牙科植入物仍然在20年内失效。此外，许多患者在手术过程中或恢复过程中感染。这些问题表明需要针对金属植入物增材制造应用优化新的表面改性工艺**。**该项目旨在开发新的表面改性技术，与Liburdis基于直接能量沉积的增材制造技术兼容。拟议的项目将侧重于表面修饰方法，将1)通过激光加工选择性地产生**先进的表面形态，以改善骨整合；2)使用聚合物基表面修饰减少术后感染/炎症反应。将这些技术开发与**定制种植体设计、种植体生产、手术计划和术后管理相结合，将形成一个完整的医疗**种植体解决方案，这将导致Liburdi的新产品，并最终使种植体接受者受益。**.**安大略省

Developing customized implants with successful bone integration is important for dental, maxillofacial, and orthopedic care in**Ontario. Liburdi has a unique direct energy deposition (DED) based additive manufacturing (AM), or 3D printing, technology that**can be further developed to efficiently produce highly customized/personalized implants on demand.**While metallic implants have become common place in dentistry and joint replacement surgeries, between 10-15% of orthopedic**and 2% of dental implants that bond to bone still fail in service within 20 years. In addition, many patients had infections from the**surgical procedures or during recovery. These problems demonstrate the need for novel surface modification processes optimized**for the additive manufacturing of metallic implant applications.**This project aims to develop new surface modification techniques that are compatible with Liburdis direct energy deposition**based AM technologies. The proposed project will focus on surface modification approaches that will 1) selectively produce**advanced surface morphology by laser machining for improved osseointegration; and 2) reduce post-surgery**infection/inflammatory response using polymer based surface modification. Integration of such technology development with**customized implant design, implant production, surgical planning, and post-surgery management will lead to a complete medical**implant solution, which will lead to a new product by Liburdi and ultimately benefit implant recipients.**.**Ontario