Assessing the potential genotoxic effect of municipal wastewater effluent treated by Advanced Oxidation System (AOS)

BioLargo Water Inc.开发的高级氧化系统（AOS）是一种很有前途的水处理技术，用于消毒和去除城市污水中的复杂有机物。该系统利用了电化学对碘化钾盐的操纵，电解，以及膨胀石墨对**的吸附功能。有证据表明，可能形成碘化和氧化物质，这可能有助于**的消毒和净化效果。然而，作为处理的副产物，潜在的反应中间体和**潜在的遗传毒性碘化有机物的形成已被提出。接触**AOS处理过的水的影响需要进一步调查，以证明该**过程的有效性和环境安全性。拟议的研究将检查基因毒物，特别是在AOS处理过的水中产生的碘化有机物是否会对水生生物产生任何不利影响。第二个目标是证明AOS是否减轻了已知基因毒物苯并-a-芘产生的基因毒性效应。拟议项目的总体目标是对这项**有前途的技术进行科学评估，并帮助BioLargo Water Inc.了解这项技术的功效，同时**确保这项技术对环境和人类健康的安全性，从而为加拿大提供经济和**环境效益。

The Advanced Oxidation System (AOS) developed by BioLargo Water Inc. is a promising water treatment**technology for disinfection and removal of complex organics from municipal effluents. The system utilizes the**electrochemical manipulation of potassium iodide salt, electrolysis, and expanded graphite adsorption to**function. Evidence suggests the potential formation of iodinated and oxidative species, which likely contribute**to the disinfection and decontamination efficacy. However, the potential formation of reactive intermediate and**potentially genotoxic iodinated organics as by-products of treatment has been raised. The effect of exposure to**AOS treated waters requires further investigation to demonstrate both efficacy and environmental safety of this**process. The proposed study will examine whether genotoxicants, especially iodinated organics generated in**the AOS treated water results in any adverse effect(s) on aquatic organisms. The second objective is to**demonstrate if AOS provides mitigation of genotoxic effects derived from a known genotoxicant,**benzo-a-pyrene. The overall aim of the proposed project is to provide a science-based assessment on this**promising technology and aid BioLargo Water Inc. in understanding the efficacy of this technology while**ensuring the safety of this technology to the environment and human health, thereby providing economic and**environmental benefits to Canada.