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A novel mechanism of reactive oxygen species-induced synthetic lethality in lung cancer

A novel mechanism of reactive oxygen species-induced synthetic lethality in lung cancer
活性氧诱导肺癌合成致死的新机制
批准号:
404170
负责人:
Johnson Fraser
金额:
$7.65万
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-10-01 至 2021-10-01

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中文摘要
翻译
肺癌是全球癌症死亡的主要原因,主要是由于缺乏有效的药物。该项目研究了一种抑制肺癌细胞的新方法,重点是利用癌症无法平衡一种称为
英文摘要
Lung cancer is the leading cause of cancer death worldwide, mainly due to the lack of effective drugs available. This project studies a new way to inhibit lung cancer cells that focuses on exploiting cancer's inability to balance a chemical process called
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Identifying genetic factors that determine responsiveness to therapeutic HIF2a pathway inactivation in Birt-Hogg-Dubé syndrome-associated renal cell carcinoma
Inhibiting lung cancer by targeting disulfide reductase enzymes with a novel small molecule that induces reactive oxygen species
The maternal embryonic leucine zipper kinase as a therapeutic target in castration-resistant prostate cancer
  • 批准号:
    367163
  • 项目类别:
    Studentship Programs
  • 资助金额:
    $1.27万
  • 财政年份:
    2016
  • 负责人:
    Johnson Fraser
  • 依托单位:
海外基金