Controlled release of functional lactoferrin from non-animal sourced matrix materials.

提高药物和天然保健品的生物利用度是营养保健品行业的一个主要障碍。尽管有明显的健康益处，但由于目前的递送技术无法确保其生物利用度、溶解度和吸收，一些候选分子没有被追求。特别是，我们对控制乳铁蛋白（一种牛奶血红素蛋白）的释放感兴趣。此外，该行业还受到用户群体的阻碍，他们希望避免使用传统的药物释放矩阵(即。聚合物)，以获得更生物/天然的材料。Unsworth教授在处理由非动物来源的合成肽组成的基质以及控制蛋白质释放方面拥有丰富而关键的经验。因此，我们正在共同努力开发一种系统来控制乳铁蛋白的功能释放，从而开发出功能性产品。

Improving the bioavailability of drugs and natural health products is a major hurdle in the nutraceutical industry. Despite the obvious health benefits, several candidate molecules are not pursued due to the inability of current delivery techniques to ensure their bioavailability, solubility and absorption. In particular, we are interested in controlling lactoferrin (a milk heme protein) release. Moreover, the industry is hindered by the community of users who want to avoid traditional matrices for releasing drugs (ie. polymers) for a more bio/natural material. Professor Unsworth has extensive and critical experience working with matrices composed of synthetic peptides from non-animal sources, as well as the controlled release of proteins. Thus, we are working together to develop a system to control the functional release of lactoferrin so as to develop a functional product.