Miniaturized Biomedical Devices

预计即时诊断系统将把目前在集中实验室进行的复杂疾病诊断和筛查测试带到患者所在地，从而显著提高医疗保健质量。然而，用于癌症、传染病、遗传病等的诊断、预后和治疗选择的商业化系统很少。提出的研究有望通过采用基于墨水的制造方法来创造具有生物受体功能化的结构调谐固相电子器件，从而改变这些系统的制造方式。这将允许用于处理临床样品和检测遗传标记的多种生物医学设备小型化，并在一个可扩展且廉价的系统上创建。

Point-of-care diagnostic systems are envisioned to significantly improve the quality of healthcare by bringing complex disease diagnostic and screening tests, currently performed at centralized laboratories, to patients locations. However, only a few systems have been commercialized for diagnosis, prognosis, and treatment selection of cancers, infectious diseases, hereditary disease, etc. The proposed research is expected to transform the way these systems are manufactured by employing ink-based fabrication methods to create structurally-tuned solid-phase electronics functionalized with bio-receptors. This will allow multiple biomedical devices for processing clinical samples and detecting genetic markers to be miniaturized and created on a single scalable and inexpensive system.