Optimization of topical formulations for the treatment of basal cell carcinoma using the Feldan Shuttle technology

这项ARD提案旨在验证治疗皮肤癌的新专利药物配方的有效性。在这项研究项目中，将使用和验证临床前模型来证明该配方的有效性以及与非配方治疗相比的优越性。该项目将通过解决皮肤涂抹治疗方面的技术问题，大力支持支持合作伙伴，这将大大增强他们的投资组合，以支持他们的经济增长和目标市场。此外，这些制剂可能为患有基底细胞癌或称为戈林综合征的遗传综合征的患者提供显著改善，这些患者复发的肿瘤损害导致需要进行有问题的系列手术或具有不良反应的系统治疗。

This ARD proposal aims at validating the efficiency of new proprietary drug formulations for the treatment of skin cancers. In this research project, a preclinical model will be used and validated to demonstrate the efficacy of the formulation as well as its superiority compared to non-formulated treatment. This project will strongly support the supporting partner by addressing technical questions in the context of skin-applied treatments that will enhance significantly their portfolio to support their economic growth and target markets. Moreover, these formulations may provide significant improvement for patients having basal cell carcinoma or the genetic syndrome termed Gorlin Syndrome where recurrent tumoral lesions are occurring leading to problematic need for serial surgery or systemic treatment with adverse effects.