Epigenetic integration of genomic and environmental information in honey bees

环境因素，如营养、药物或童年疏忽，在不改变DNA密码的情况下改变基因活性，并可能导致一系列疾病，如癌症、肥胖症和精神疾病。这种表观遗传现象是由被称为DNA甲基化的基因组微妙且鲜为人知的修改所驱动的。我们的目标是研究DNA甲基化和环境影响之间的联系。我们渴望了解环境信号如何触发基因网络转录控制的重新编程，从而使用蜜蜂模型产生不同的表型和行为结果

Environmental factors such as nutrition, drugs or childhood neglect alter gene activity without a change to the DNA code and may result in a range of conditions such as cancer, obesity and mental illness. Such epigenetic phenomena are driven by subtle and poorly understood modifications of the genome known as DNA methylation. Our aim is to study the link between DNA methylation and environmental influences. We aspire to understand how environmental signals trigger the reprogramming of transcriptional control of genetic networks that lead to contrasting phenotypic and behavioural outcomes using the honey bee model