Ikirara, a novel transposon family from the malaria vector mosquito, Anopheles gambiae

Ikirara, a novel transposon family from the malaria vector mosquito, Anopheles gambiae
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Ikirara,来自疟疾媒介蚊子冈比亚按蚊的新型转座子家族

DOI:
10.1046/j.1365-2583.1998.71046.x
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发表时间:
1998
影响因子:
2.6
通讯作者:
A. Colavita
A. Colavita
中科院分区:
农林科学2区
文献类型:
--
作者:
P. Romans;R. Bhattacharyya;A. Colavita

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在疟疾载体冈比亚按蚊的基因组中发现了一种新型转座子家族 Ikirara 的成员。它们在 A. gambiae sensu stricto 中最为丰富,但在该物种复合体的所有其他四个测试成员中都发现了相关序列。在 A. funestus 或 A. stephensi 中没有发现亲属。 Ikirara1 是第一个分离的家族成员,被发现于两个串联卵黄蛋白原 (Vg) 基因之间。因为它是在 G3 的这个位置发现的,并且是其他九个冈比亚 A. gambiae s.s. 中的一个。检查菌株,并且由于其 216 bp 反向末端重复序列 100% 相同,因此转座到该基因座可能是最近发生的。 Ikirara1 反向重复末端序列与 mariner/Tc1 和 hAT 超家族的 DNA 到 DNA 转座子的序列相似。与 mariner/Tc1 元件类似,Ikirara1 的插入显然在靶位点产生了二核苷酸 TA 的重复。
Members of a novel transposon family, Ikirara, were found in the genome of the malaria vector Anopheles gambiae. They are most abundant in A. gambiae sensu stricto, but related sequences were found in all four other tested members of this species complex. No relatives were found in A. funestus or A. stephensi. Ikirara1, the first isolated family member, was found between two of the tandem Vitellogenin (Vg) genes. Because it was found at this location in G3 and only one of nine other A. gambiae s.s. strains examined, and because its 216 bp inverted terminal repeats are 100% identical, transposition to this locus may have been recent. Ikirara1 inverted repeat terminal sequences are similar to those of DNA to DNA transposons of the mariner/Tc1 and hAT superfamilies. Also similar to mariner/Tc1 elements, insertion of Ikirara1 apparently created a duplication of the dinucleotide TA at the target site.
DOI: 10.1093/nar/11.12.4201
发表时间: 1983-06
影响因子: 14.9
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发表时间: 1994
期刊: Genetical research
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发表时间: 1988
影响因子: 5.3
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