Outdoor green space exposure and brain health measures related to Alzheimer's disease: a rapid review.

Outdoor green space exposure and brain health measures related to Alzheimer's disease: a rapid review.
复制标题

DOI:
10.1136/bmjopen-2020-043456
复制
发表时间:
2021-05-03
期刊:
影响因子:
2.9
通讯作者:
Besser L
Besser L
中科院分区:
医学3区
文献类型:
--
作者:
Besser L

文献摘要

参考文献

被引文献

相似文献

总结与阿尔茨海默病及相关疾病(ADRD)相关的户外绿地暴露和脑健康措施的研究,并确定未来研究的科学空白。快速审查主要研究报告。应用计算机检索PubMed、Embase和Web of Science Core Collection,检索符合2020年2月13日之前发表的标准的文章。这篇综述排除了非英语的论文,这些论文集中在短暂的状态(例如,精神疲劳),或者没有使用个人水平的大脑健康衡量标准(例如,学校平均考试成绩)。感兴趣的大脑健康指标包括认知功能、认知障碍/痴呆症/ADRD的临床诊断以及脑生物标记物,如MRI中的那些,通常与ADRD风险和疾病进展相关的指标。2012年至2020年共发表了22篇论文,其中36%是关于18岁,32%是关于18-,59%是关于≥,65岁。64%的人根据归一化植被指数(绿色/健康植被)来定义绿地,68%的人关注大脑健康的认知指标(如记忆力)。17项研究(77%)发现了绿色空间与大脑健康的联系(14项阳性,4项相反)。在10项研究中,更大的绿度/绿地与不同的认知域正相关,在3项研究中,更大的绿度/绿地与MRI结果(区域脑体积、皮质厚度、杏仁核完整性)呈正相关。在一些研究中,社区绿色度越高,认知损害/ADRD的几率/风险就越低,但在其他研究中,认知损害/ADRD的几率/风险就越高(n=4项研究)。已发表的研究表明,在整个生命过程中,绿地与大脑健康之间存在积极的联系,但方法和队列有限且不同。未来的研究将使用种族/民族和地理上不同的队列、生命过程方法以及更具体的绿地和大脑健康指标(例如,在绿地度过的时间、ADRD生物标记物),将加强因果关系的证据。
Summarise studies of outdoor green space exposure and brain health measures related to Alzheimer’s disease and related disorders (ADRD), and determine scientific gaps for future research. Rapid review of primary research studies. PubMed, Embase and Web of Science Core Collection were searched for articles meeting the criteria published on/before 13 February 2020. The review excluded papers not in English, focused on transient states (eg, mental fatigue) or not using individual-level measures of brain health (eg, average school test scores). Brain health measures of interest included cognitive function, clinical diagnosis of cognitive impairment/dementia/ADRD and brain biomarkers such as those from MRI, measures typically associated with ADRD risk and disease progression. Twenty-two papers were published from 2012 to 2020, 36% on <18 years old, 32% on 18–64 years old and 59% on ≥65 years old. Sixty-four per cent defined green space based on the Normalised Difference Vegetation Index (‘greenness’/healthy vegetation) and 68% focused on cognitive measures of brain health (eg, memory). Seventeen studies (77%) found green space-brain health associations (14 positive, 4 inverse). Greater greenness/green space was positively associated various cognitive domains in 10 studies and with MRI outcomes (regional brain volumes, cortical thickness, amygdala integrity) in three studies. Greater neighbourhood greenness was associated with lower odds/risk of cognitive impairment/ADRD in some studies but increased odds/risk in others (n=4 studies). Published studies suggest positive green space-brain health associations across the life course, but the methods and cohorts were limited and heterogeneous. Future research using racially/ethnically and geographically diverse cohorts, life course methods and more specific green space and brain health measures (eg, time spent in green spaces, ADRD biomarkers) will strengthen evidence for causal associations.
DOI: 10.1289/ehp694
发表时间: 2017-09-18
影响因子: 10.4
作者:
Dadvand P;Tischer C;Estarlich M;Llop S;Dalmau-Bueno A;López-Vicente M;Valentín A;de Keijzer C;Fernández-Somoano A;Lertxundi N;Rodriguez-Dehli C;Gascon M;Guxens M;Zugna D;Basagaña X;Nieuwenhuijsen MJ;Ibarluzea J;Ballester F;Sunyer J
通讯作者: Sunyer J
DOI: 10.3233/jad-170658
发表时间: 2018
期刊: Journal of Alzheimer's disease : JAD
影响因子: --
作者:
Cleary EG;Cifuentes M;Grinstein G;Brugge D;Shea TB
通讯作者: Shea TB
DOI: 10.1016/j.socscimed.2017.10.038
发表时间: 2018-01-01
影响因子: 5.4
作者:
Cherrie, Mark P. C.;Shortt, Niamh K.;Pearce, Jamie R.
通讯作者: Pearce, Jamie R.
DOI: 10.1073/pnas.1015950108
发表时间: 2011-02-15
影响因子: 11.1
作者:
Erickson, Kirk I.;Voss, Michelle W.;Kramer, Arthur F.
通讯作者: Kramer, Arthur F.
DOI: 10.1097/wad.0b013e3182163b62
发表时间: 2012-01
影响因子: 2.1
作者:
Apostolova LG;Green AE;Babakchanian S;Hwang KS;Chou YY;Toga AW;Thompson PM
通讯作者: Thompson PM