The Materiobiology of Silk: Exploring the Biophysical Influence of Silk Biomaterials on Directing Cellular Behaviors.

The Materiobiology of Silk: Exploring the Biophysical Influence of Silk Biomaterials on Directing Cellular Behaviors.
复制标题

丝绸的产生生物学:探索丝绸生物材料对指导细胞行为的生物物理影响。

DOI:
10.3389/fbioe.2021.697981
复制
发表时间:
2021
影响因子:
5.7
通讯作者:
Abbott RD
Abbott RD
中科院分区:
工程技术2区
文献类型:
--
作者:
Kochhar D;DeBari MK;Abbott RD

文献摘要

参考文献

被引文献

相似文献

细胞外环境的生物物理性质在这次综述中动态调节细胞命运,这是由于其独特的机械性能,生物活性的序列,可降解性,降解性,定义良好的体系结构和生物兼容性的元素构造,这是一种不可或缺的聚合物生物材料。基于非叶毛,影响细胞行为,包括细胞粘附,细胞增殖,细胞迁移和细胞分化。考虑到丝,纤维或赞助商形式的丝绸的新型生物物理特性,再加上易于的化学装饰,及其对特定组织的功能要求匹配的能力,我们调查了组成,机械性能,形状,地形和续约的势头的影响。
Biophysical properties of the extracellular environment dynamically regulate cellular fates. In this review, we highlight silk, an indispensable polymeric biomaterial, owing to its unique mechanical properties, bioactive component sequestration, degradability, well-defined architectures, and biocompatibility that can regulate temporospatial biochemical and biophysical responses. We explore how the materiobiology of silks, both mulberry and non-mulberry based, affect cell behaviors including cell adhesion, cell proliferation, cell migration, and cell differentiation. Keeping in mind the novel biophysical properties of silk in film, fiber, or sponge forms, coupled with facile chemical decoration, and its ability to match functional requirements for specific tissues, we survey the influence of composition, mechanical properties, topography, and 3D geometry in unlocking the body’s inherent regenerative potential.
DOI: 10.1002/adhm.201600211
发表时间: 2016-07
影响因子: 10
作者:
Abbott RD;Wang RY;Reagan MR;Chen Y;Borowsky FE;Zieba A;Marra KG;Rubin JP;Ghobrial IM;Kaplan DL
通讯作者: Kaplan DL
DOI: 10.1371/journal.pone.0109770
发表时间: 2014
期刊: PloS one
影响因子: 3.7
作者:
Dinis TM;Vidal G;Jose RR;Vigneron P;Bresson D;Fitzpatrick V;Marin F;Kaplan DL;Egles C
通讯作者: Egles C
DOI: 10.1021/acsami.6b08180
发表时间: 2016-09-21
影响因子: 9.5
作者:
Ding, Zhaozhao;Fan, Zhihai;Kaplan, David L.
通讯作者: Kaplan, David L.
DOI: 10.1126/science.1064829
发表时间: 2001-11-23
期刊: SCIENCE
影响因子: 56.9
作者:
Cukierman, E;Pankov, R;Yamada, KM
通讯作者: Yamada, KM
DOI: 10.1021/am4060595
发表时间: 2014-04-09
影响因子: 9.5
作者:
Dhyani, Vartika;Singh, Neetu
通讯作者: Singh, Neetu