Relations between mucosal immunity and children's mental health: the role of child sex.

Relations between mucosal immunity and children's mental health: the role of child sex.
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DOI:
10.1016/j.physbeh.2010.08.012
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发表时间:
2010-12-02
影响因子:
2.9
通讯作者:
Granger, Douglas A.
Granger, Douglas A.
中科院分区:
医学3区
文献类型:
--
作者:
Keller, Peggy S.;El-Sheikh, Mona;Vaughn, Brian;Granger, Douglas A.

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本研究探讨儿童唾液白细胞介素-6 (IL-6)和分泌性免疫球蛋白A (SIgA)与心理健康的关系。儿童性行为被认为是关系的缓和剂。数据来自329名正常发育儿童(M年龄= 9.85岁,SD = 0.98岁);67%的儿童是欧洲裔美国人,33%是非洲裔美国人。下午采集唾液样本,检测SIgA和IL-6。父母完成了儿童内化和外化症状的问卷测量,儿童完成了焦虑和抑郁的自我报告测量。结构方程模型拟合数据,表明唾液IL-6和SIgA水平较高与女孩适应问题的关系比男孩更强。
This study examines relations between children’s salivary interleukin-6 (IL-6) and secretory immunoglobulin A (SIgA) and mental health. Child sex was considered as a moderator of relations. Data were from 329 normally-developing children (M age = 9.85 years; SD = 0.98 years); 67% of children were European American and 33% were African American. Saliva samples were obtained during the afternoon and assayed for SIgA and IL-6. Parents completed questionnaire measures of child internalizing and externalizing symptoms, and children completed self-report measures of anxiety and depression. Structural equation models were fit to the data, and indicated that greater levels of salivary IL-6 and SIgA were associated with adjustment problems more strongly for girls than for boys.
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发表时间: 2009-05
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