Impact of REM sleep on distortions of self-concept, mood and memory in depressed/anxious participants.
Impact of REM sleep on distortions of self-concept, mood and memory in depressed/anxious participants.
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DOI：
10.1016/j.jad.2009.06.030
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发表时间：
2010-05
影响因子：
6.6
通讯作者：
Doros, Gheorghe
中科院分区：
文献类型：
--
作者：
McNamara, Patrick;Auerbach, Sanford;Johnson, Patricia;Harris, Erica;Doros, Gheorghe
我们验证了快速眼动睡眠与焦虑抑郁症认知功能障碍的核心特征有关的假设，包括消极的自我评价、偏颇的记忆加工和不愉快的梦内容。在睡眠实验室度过一个习惯的夜晚后，35名健康的大学生和20名抑郁/焦虑的学生被叫醒，进入快速眼动睡眠10分钟，然后进入非快速眼动睡眠10分钟。为了控制昼夜节律的影响，唤醒被平衡了。每次醒来后，参与者都会报告一个梦，然后完成回忆、情绪和自我评估任务。在快速眼动睡眠和非快速眼动睡眠中醒来后，抑郁/焦虑参与者的自我评价显著减少，显著增加消极。只有抑郁/焦虑受试者对快速眼动睡眠梦境自我的评价为阴性。无论是抑郁/焦虑的参与者还是健康的参与者，在快速眼动和非快速眼动睡眠醒来后，消极记忆的回忆都明显更频繁。与非快速眼动睡眠的参与者相比，抑郁/焦虑的参与者在快速眼动睡眠中的梦境与更高频率的负面情绪、更大的攻击性和受害率相关。抑郁/焦虑的参与者是根据情绪量表而不是临床访谈来分类的。所有的参与者都是从大学生志愿者人群中抽取的，因此我们的结果可能不适用于一些老年临床人群。快速眼动似乎促进了焦虑抑郁的认知扭曲。
We tested the hypothesis that REM sleep contributes to core features of cognitive dysfunction of anxious depression including negative self-appraisals, biased memory processing and unpleasant dream content. After a habituation night in a sleep lab, a convenience sample of 35 healthy college students and 20 depressed/anxious students were awakened 10 minutes into a REM sleep episode and then 10 minutes into a NREM sleep episode. Awakenings were counterbalanced to control circadian effects. After each awakening participants reported a dream and then completed memory recall, mood and self-appraisal tasks. Self-appraisals of depressed/anxious participants were significantly less positive and significantly more negative after awakenings from REM sleep vs NREM sleep. Appraisal of the REM sleep dream self was negative for depressed/anxious subjects only. Recall of negative memories was significantly more frequent after REM vs NREM sleep awakenings for both depress/anxious and healthy participants. REM sleep dreams were associated with greater frequencies of negative emotion, greater aggression and victimization rates than dreams in NREM sleep for depressed/anxious participants. Depressed/anxious participants were classified as such on the basis of mood scales rather than clinical interview. All participants were drawn from a volunteer college student population and thus our results may not be applicable to some elderly clinical populations. REM appears to facilitate cognitive distortions of anxious depression.
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影响因子：
10.6
作者：
Davidson, RJ
通讯作者：
Davidson, RJ
影响因子：
4.1
作者：
BRADLEY, BP;MOGG, K;WILLIAMS, R
通讯作者：
WILLIAMS, R
影响因子：
6.7
作者：
Armitage, R.
通讯作者：
Armitage, R.
DOI：
10.1196/annals.1314.020
发表时间：
2004-01-01
期刊：
BIOBEHAVIORAL STRESS RESPONSE: PROTECTIVE AND DAMAGING EFFECTS
影响因子：
--
作者：
Born, J;Wagner, U
通讯作者：
Wagner, U
影响因子：
3.3
作者：
Cacioppo, JT;Hawkley, LC;Berntson, GG
通讯作者：
Berntson, GG