Altered spontaneous activity in young chronic cigarette smokers revealed by regional homogeneity.
Altered spontaneous activity in young chronic cigarette smokers revealed by regional homogeneity.
复制标题
区域同质性揭示年轻长期吸烟者自发活动的改变
DOI:
10.1186/1744-9081-8-44
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发表时间:
2012-08-22
期刊:
影响因子:
--
通讯作者:
Hao W
中科院分区:
文献类型:
--
作者:
Tang J;Liao Y;Deng Q;Liu T;Chen X;Wang X;Xiang X;Chen H;Hao W
BackgroundFew studies have been previously published about the resting state brain activity in young chronic smokers, although many previous fMRI studies have shown that the task-related activity pattern is altered in chronic smokers.MethodsIn the present study, forty-five healthy smokers (age: 27.9 ± 5.6 year) and forty-four healthy non-smoking control subjects (age: 26.3 ± 5.8 year) have been imaged with functional magnetic resonance imaging (fMRI) and analyzed with the regional homogeneity (ReHo) approach.ResultsCompared with healthy controls, decreased ReHo was found in smokers in the right inferior frontal cortex and increased ReHo was found in the left superior parietal lobe (P < 0.01, 35 Voxels,Alphasim corrected).ConclusionsOur data suggested that, during resting state, neural function is less synchronized in the right inferior frontal cortex and more synchronized in the left superior parietal lobe in chronic smokers compared to non-smokers. The decreased synchronization in the right inferior frontal cortex may reflect lacking of control over reward-related behavior, and the increased synchronization may reflect smoking urges.
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影响因子:
3.7
作者:
Song XW;Dong ZY;Long XY;Li SF;Zuo XN;Zhu CZ;He Y;Yan CG;Zang YF
通讯作者:
Zang YF
影响因子:
3.4
作者:
Yu, Rongjun;Zhao, Liyan;Lu, Lin
通讯作者:
Lu, Lin
影响因子:
3.7
作者:
Liao Y;Tang J;Deng Q;Deng Y;Luo T;Wang X;Chen H;Liu T;Chen X;Brody AL;Hao W
通讯作者:
Hao W
DOI:
10.1023/a:1024190429920
发表时间:
2002-03-01
期刊:
JOURNAL OF NEUROCYTOLOGY
影响因子:
--
作者:
Fuster, JM
通讯作者:
Fuster, JM
影响因子:
8.2
作者:
Liu, Xun;Hairston, Jacqueline;Schrier, Madeleine;Fan, Jin
通讯作者:
Fan, Jin