Distribution and molecular characterization of avian infectious bronchitis virus in southern China.
Distribution and molecular characterization of avian infectious bronchitis virus in southern China.
复制标题
中国南方禽传染性支气管炎病毒的分布及分子特征
DOI：
10.1016/j.psj.2021.101169
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发表时间：
2021-07
期刊：
影响因子：
4.4
通讯作者：
Lin W
中科院分区：
文献类型：
--
作者：
Lian J;Wang Z;Xu Z;Chen T;Shao G;Zhang X;Qin J;Xie Q;Lin W
禽传染性支气管炎病毒(IBV)给世界养禽业造成了巨大的经济损失。该病的主要防控难点是众多的基因和血清型。IBV的遗传分析主要基于在传染性中起重要作用的S1基因。本研究从2019年4月至2020年3月期间，从中国南部地区出现疾病征兆的鸡群中分离到139株禽传染性支气管炎病毒。将分离的野毒株的核苷酸和氨基酸序列与22篇文献进行了比较。核苷酸同源性为64.5%~100%，氨基酸同源性为70%~99.8%。6株不同基因型的鸡传染性支气管炎病毒在中国南部地区同时流行。QX型仍然是最主要的显性基因。对S1基因的核苷酸和氨基酸序列进行比对，发现S1基因的替换、插入和缺失在分离株中广泛存在。重组分析表明，这些菌株之间存在大量的重组菌株，形成了新的亚分支、亚型和变异体。因此，长期持续监测是预防和控制IBV的必要手段。
Avian infectious bronchitis virus (IBV) is causing considerable economic losses in the world poultry industry. The main difficulty of prevention and control of IB disease is the numerous genotypes and serotypes. The genetic analysis of IBV was mainly based on the S1 gene which played an important role in infectivity. In the study, One hundred and thirty-nine strains of avian infectious bronchitis virus were isolated from chickens showing signs of disease in southern China during the period from April 2019 to March 2020. The nucleotide and amino acid sequences from the isolated field strains were compared to 22 published references. Nucleotide homologies ranged from 64.5% to 100% and amino acid homologies ranging from 70% to 99.8%. Six genotype IBV strains were co-circulating in southern China. QX-type was still the most dominant genotype. Alignment of nucleotide and amino acid sequences of S1 gene revealed that the substitutions, insertions and deletions are widely among isolated strains. Recombination analysis showed that there is a large number of recombinant strains amongst these isolates, forming new sub branches, subtypes and variants. Therefore, long-term continuing surveillance is necessary for IBV prevention and control.
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DOI：
10.1016/j.meegid.2011.01.007
发表时间：
2011-04
期刊：
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
影响因子：
--
作者：
Lim TH;Lee HJ;Lee DH;Lee YN;Park JK;Youn HN;Kim MS;Lee JB;Park SY;Choi IS;Song CS
通讯作者：
Song CS
影响因子：
3.8
作者：
KOCH, G;HARTOG, L;VANROOZELAAR, DJ
通讯作者：
VANROOZELAAR, DJ
影响因子：
4.8
作者：
Ji J;Xie J;Chen F;Shu D;Zuo K;Xue C;Qin J;Li H;Bi Y;Ma J;Xie Q
通讯作者：
Xie Q
影响因子：
5
作者：
Lee, CW;Jackwood, MW
通讯作者：
Jackwood, MW
影响因子：
4.6
作者：
Liu, Shengwang;Zhang, Xiaonan;Kong, Xiangang
通讯作者：
Kong, Xiangang