Nanoscaled Zinc Oxide Prepared by Mono-amino Acid Templated Assembly and Their Superior Biological Properties
Nanoscaled Zinc Oxide Prepared by Mono-amino Acid Templated Assembly and Their Superior Biological Properties
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单氨基酸模板组装制备纳米氧化锌及其优越的生物性能
DOI：
10.1007/s10876-021-01986-w
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发表时间：
2021-01
期刊：
影响因子：
--
通讯作者：
Hui Liu
中科院分区：
文献类型：
--
作者：
Chengfang Tan;Zhiyin Sun;Ying Ruan;Yisheng Cui;Gege Zuo;Peng Yu;Hui Liu
以单氨基酸为模板，通过良性矿化反应合成了纳米氧化锌（ZnO）。通过傅里叶变换红外光谱、x射线衍射和扫描电镜对ZnO的微观结构进行了表征，发现制备的ZnO可以分别被亮氨酸和组氨酸微调成橄榄状和片状结构。此外，光致发光（PL）结果表明，生物矿化ZnO纳米颗粒在光学器件领域具有潜在的应用前景。为了进一步探索ZnO纳米颗粒的生物学性能，我们还研究了ZnO纳米颗粒对金黄色葡萄球菌和大肠杆菌的抑菌活性以及对小鼠MC3T3细胞的细胞相容性。这些生物矿化氧化锌优越的生物学特性及其固有的光致发光特性为生物医学应用的发展开辟了前景。
Nanoscaled zinc oxide (ZnO) was synthesized via a benign mineralization reaction using mono-amino acid as templates. Characterized by Fourier transform infrared spectroscopy, X-ray diffraction, and scanning electron microscopy, it was found that the microstructure of as-prepared ZnO can be fine-tuned into olive-like and flake-like structures with leucine and histidine respectively. Otherwise, the photoluminescence (PL) results indicate that biomineralized ZnO nanoparticles show a potential application in the fields of optical devices. To further explore the biological performance of as-prepared ZnO nanoparticles, antibacterial activity tests againstStaphylococcus aureusandEscherichia coli, and cytocompatibility on mouse MC3T3 cells were also investigated. The superior biological properties of these biomineralized ZnO together with their intrinsic photoluminescent properties open perspectives for the development of biomedical applications.
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DOI：
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发表时间：
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