Construction and validation of a database of head models for functional imaging of the neonatal brain.
Construction and validation of a database of head models for functional imaging of the neonatal brain.
复制标题
新生儿脑功能成像头部模型数据库的构建与验证。
DOI：
10.1002/hbm.25242
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发表时间：
2021-02-15
影响因子：
4.8
通讯作者：
Cooper RJ
中科院分区：
文献类型：
--
作者：
Collins-Jones LH;Arichi T;Poppe T;Billing A;Xiao J;Fabrizi L;Brigadoi S;Hebden JC;Elwell CE;Cooper RJ
新生儿的大脑在妊娠的最后三个月经历了巨大的结构和功能变化。因此，从头皮记录的大脑活动的源定位的准确性依赖于准确的特定年龄的头部模型。虽然可以使用适合年龄的人群水平图谱，但在构建此类图谱时丢失了细节，特别是关于皮质表面的平滑，因此此类模型不能代表个体水平的解剖结构。在这项工作中，我们描述了新生儿头部个体结构先验数据库的构建，使用了来自发育中人类连接组项目的215个个体水平数据集，年龄为月经后29-44周。我们已经验证了一种分割脑外组织的方法，而不是手动分割。我们还进行了留一分析，以量化当使用数据库中的最佳匹配个体代替受试者特定模型时，在定位功能激活方面产生的预期空间误差;计算的中位误差为8.3 mm（中位绝对偏差3.8 mm）。该数据库可以应用于任何功能性神经成像模态，其需要结构数据，由此与该模态相关的物理参数随组织类型而变化，并且可以在www.ucl.ac.uk/dot-hub上免费获得。当没有受试者特定的结构数据时，从头皮记录的大脑活动源定位的准确性依赖于准确的年龄特定的头部模型。在这项工作中，我们描述了新生儿头部个体结构先验数据库的构建，使用了来自发育中人类连接组项目的215个个体水平数据集，年龄为月经后29-44周。我们还提供了留一分析的结果，以验证使用数据库中的匹配模型代替受试者特定模型的准确性。
The neonatal brain undergoes dramatic structural and functional changes over the last trimester of gestation. The accuracy of source localisation of brain activity recorded from the scalp therefore relies on accurate age‐specific head models. Although an age‐appropriate population‐level atlas could be used, detail is lost in the construction of such atlases, in particular with regard to the smoothing of the cortical surface, and so such a model is not representative of anatomy at an individual level. In this work, we describe the construction of a database of individual structural priors of the neonatal head using 215 individual‐level datasets at ages 29–44 weeks postmenstrual age from the Developing Human Connectome Project. We have validated a method to segment the extra‐cerebral tissue against manual segmentation. We have also conducted a leave‐one‐out analysis to quantify the expected spatial error incurred with regard to localising functional activation when using a best‐matching individual from the database in place of a subject‐specific model; the median error was calculated to be 8.3 mm (median absolute deviation 3.8 mm). The database can be applied for any functional neuroimaging modality which requires structural data whereby the physical parameters associated with that modality vary with tissue type and is freely available at www.ucl.ac.uk/dot-hub. When no subject‐specific structural data are available, the accuracy of source localisation of brain activity recorded from the scalp relies on accurate age‐specific head models. In this work, we describe the construction of a database of individual structural priors of the neonatal head using 215 individual‐level datasets at ages 29–44 weeks postmenstrual age from the Developing Human Connectome Project. We also present the results of a leave‐one‐out analysis to validate the accuracy of using a matched model from the database in place of a subject‐specific model.
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DOI：
10.1093/cercor/bhy050
发表时间：
2018-07-01
期刊：
Cerebral cortex (New York, N.Y. : 1991)
影响因子：
--
作者：
Dall'Orso S;Steinweg J;Allievi AG;Edwards AD;Burdet E;Arichi T
通讯作者：
Arichi T
影响因子：
5.7
作者：
Austin, T.;Gibson, A. P.;Hebden, J. C.
通讯作者：
Hebden, J. C.
影响因子：
4.8
作者：
Dehaes, Mathieu;Kazemi, Kamran;Wallois, Fabrice
通讯作者：
Wallois, Fabrice
影响因子：
5.7
作者：
Arichi, Tomoki;Fagiolo, Gianlorenzo;Varela, Marta;Melendez-Calderon, Alejandro;Allievi, Alessandro;Merchant, Nazakat;Tusor, Nora;Counsell, Serena J.;Burdet, Etienne;Beckmann, Christian F.;Edwards, A. David
通讯作者：
Edwards, A. David
影响因子：
3.4
作者：
Dempsey LA;Persad M;Powell S;Chitnis D;Hebden JC
通讯作者：
Hebden JC